富含血小板生长因子的自体血浆在耳鼻喉科生物刺激效率的初步研究:耳科手术(I型鼓室成形术)。

ISRN surgery Pub Date : 2011-01-01 Epub Date: 2011-06-20 DOI:10.5402/2011/451020
María Luisa Navarrete Álvaro, N Ortiz, L Rodriguez, R Boemo, J F Fuentes, A Mateo, P Ortiz
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引用次数: 40

摘要

当进行涉及鼓膜修复的耳科手术时,使用与移植物一样正常的生物材料或生物组织。目前,使用来自自己患者的生物材料的成功率各不相同。使用的程序和患者的组织修复能力往往决定结果。我们提出了一项使用自体移植物修复鼓膜穿孔的初步研究,该移植物通过操纵血小板脱颗粒和凝血级联获得,并用血小板生长因子密封加固。我们介绍了三个使用此程序的案例。结果将根据鼓膜穿孔闭合指数进行评估。通过这项研究,我们希望用这种技术简单的方法来评估鼓膜穿孔修复的有效性。如果这种方法被客观地证明是有效的,它将降低患者的发病率和卫生成本。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pilot study on the efficiency of the biostimulation with autologous plasma rich in platelet growth factors in otorhinolaryngology: otologic surgery (tympanoplasty type I).

Pilot study on the efficiency of the biostimulation with autologous plasma rich in platelet growth factors in otorhinolaryngology: otologic surgery (tympanoplasty type I).

Pilot study on the efficiency of the biostimulation with autologous plasma rich in platelet growth factors in otorhinolaryngology: otologic surgery (tympanoplasty type I).

Pilot study on the efficiency of the biostimulation with autologous plasma rich in platelet growth factors in otorhinolaryngology: otologic surgery (tympanoplasty type I).

When otologic procedures that involve tympanic membrane repairs are performed, biomaterials or biological tissues as normal as grafts are used. At the moment, biological material from the own patient is used with varying success rates. The procedure used and the patient's tissue repair capabilities tend to determine the outcome. We present a preliminary study on tympanic membrane perforation repairs using an autograft obtained by manipulating platelet degranulation and the coagulation cascade and reinforced with a seal using platelet growth factors. We present three cases in which we used this procedure. The results will be valued based on the tympanic perforation closure index. With this study, we want to assess the effectiveness of tympanic perforation repairs with this technically simple method. If this method was objectively proved to be effective, it would lead to lower patient morbidity and sanitary costs.

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