老年人对药物作用的认识

Line Guénette PhD , Jocelyne Moisan PhD
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引用次数: 19

摘要

人们普遍认为老年人对药物的作用知之甚少。然而,研究人员报告了相互矛盾的结果。此外,人们对哪些患者特征与药物用途相关知之甚少。目的评估社区居住老年人是否能正确识别其处方药和非处方药的一般用途,并检查参与者和药物特征与这一知识之间的联系。方法采用上门访谈的方式,随机抽取年龄≥65岁的药房客户,报告其在过去30天内服用的所有药物,并说明其使用药物的原因。根据解剖治疗化学(ATC)分类系统对药物进行分类。我们在陈述的原因中寻找有关解剖系统、器官和疾病的任何信息。如果陈述的原因是指药物针对的解剖系统,我们假设患者知道药物的一般用途。使用多元逻辑回归模型来识别与知识相关的参与者特征。结果共采访了193名老年人,共报告使用了1645种可按ATC分类系统分类的药物。在这些药物中,1364种(82.9%)是自我报告的医生处方。在参与者中,134人(69.4%)知道他们报告的所有药物的一般用途。与了解治疗目的相关的特征是女性(校正优势比[OR]为3.3,95%可信区间[CI]为1.5-7.1)、正常认知(校正优势比[OR]为5.0;95% CI, 2.0-12.8),以及平均到优越的社会经济地位(校正OR, 2.7, 95% CI, 1.2-6.3)。非处方药知识略好于处方药知识(合理原因总比例:96.1% vs 91.1%;P & lt;0.01)。结论社区老年人对其处方药和非处方药的一般用途有较好的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Elderly People's Knowledge of the Purpose of Their Medicines

Background

It is generally believed that elderly persons know little about the purpose of their medications. However, researchers have reported contradictory results. Moreover, little is known about which patient characteristics are associated with knowledge of a drug's purpose.

Objectives

To assess whether community-dwelling elderly persons could correctly identify the general purpose of their prescription and nonprescription drugs and to examine the link between participant and drug characteristics and this knowledge.

Methods

During an in-home interview, a random sample of pharmacy clients aged ≥65 years were asked to report all the drugs they had taken over the previous 30 days and to state the reasons for their use. Drugs were classified according to the anatomical therapeutic chemical (ATC) classification system. We looked for any information in the stated reasons that concerned the anatomical system, organs and diseases. We assumed that the person knew the general purpose of the drug if the reason stated referred to the anatomical system targeted by the drug. A multivariate logistic regression model was used to identify participant characteristics that were associated with knowledge.

Results

We interviewed 193 seniors who reported using 1645 drugs that could be classified according to the ATC classification system. Of those drugs, 1364 (82.9%) were self reported as physician prescribed. Among participants, 134 (69.4%) knew the general purpose of all drugs they reported. Characteristics associated with knowledge of the purpose were female gender (adjusted odds ratios [ORs], 3.3, 95% confidence intervals [CI] 1.5–7.1), normal cognition (adjusted OR, 5.0; 95% CI, 2.0–12.8), and average to superior socioeconomic status (adjusted OR, 2.7, 95% CI, 1.2–6.3). Knowledge was slightly better for nonprescribed drugs than for prescribed drugs (overall proportion of appropriate reasons: 96.1% vs 91.1%; P < 0.01).

Conclusions

Community-dwelling elderly persons have a good knowledge of the general purpose of their prescription and nonprescription drugs.

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来源期刊
American Journal Geriatric Pharmacotherapy
American Journal Geriatric Pharmacotherapy GERIATRICS & GERONTOLOGY-PHARMACOLOGY & PHARMACY
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