Brian W Miller, Lars R Furenlid, Stephen K Moore, H Bradford Barber, Vivek V Nagarkar, Harrison H Barrett
{"title":"基于 BazookaSPECT 探测器技术的专用 SPECT 鼠脑成像仪 FastSPECT III 的系统集成。","authors":"Brian W Miller, Lars R Furenlid, Stephen K Moore, H Bradford Barber, Vivek V Nagarkar, Harrison H Barrett","doi":"10.1109/NSSMIC.2009.5401924","DOIUrl":null,"url":null,"abstract":"<p><p>FastSPECT III is a stationary, single-photon emission computed tomography (SPECT) imager designed specifically for imaging and studying neurological pathologies in rodent brain, including Alzheimer's and Parkinsons's disease. Twenty independent BazookaSPECT [1] gamma-ray detectors acquire projections of a spherical field of view with pinholes selected for desired resolution and sensitivity. Each BazookaSPECT detector comprises a columnar CsI(Tl) scintillator, image-intensifier, optical lens, and fast-frame-rate CCD camera. Data stream back to processing computers via firewire interfaces, and heavy use of graphics processing units (GPUs) ensures that each frame of data is processed in real time to extract the images of individual gamma-ray events. Details of the system design, imaging aperture fabrication methods, and preliminary projection images are presented.</p>","PeriodicalId":73298,"journal":{"name":"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium","volume":"Oct. 24 2009-Nov. 1 2009 ","pages":"4004-4008"},"PeriodicalIF":0.0000,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017366/pdf/nihms235208.pdf","citationCount":"0","resultStr":"{\"title\":\"System Integration of FastSPECT III, a Dedicated SPECT Rodent-Brain Imager Based on BazookaSPECT Detector Technology.\",\"authors\":\"Brian W Miller, Lars R Furenlid, Stephen K Moore, H Bradford Barber, Vivek V Nagarkar, Harrison H Barrett\",\"doi\":\"10.1109/NSSMIC.2009.5401924\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>FastSPECT III is a stationary, single-photon emission computed tomography (SPECT) imager designed specifically for imaging and studying neurological pathologies in rodent brain, including Alzheimer's and Parkinsons's disease. Twenty independent BazookaSPECT [1] gamma-ray detectors acquire projections of a spherical field of view with pinholes selected for desired resolution and sensitivity. Each BazookaSPECT detector comprises a columnar CsI(Tl) scintillator, image-intensifier, optical lens, and fast-frame-rate CCD camera. Data stream back to processing computers via firewire interfaces, and heavy use of graphics processing units (GPUs) ensures that each frame of data is processed in real time to extract the images of individual gamma-ray events. Details of the system design, imaging aperture fabrication methods, and preliminary projection images are presented.</p>\",\"PeriodicalId\":73298,\"journal\":{\"name\":\"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium\",\"volume\":\"Oct. 24 2009-Nov. 1 2009 \",\"pages\":\"4004-4008\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017366/pdf/nihms235208.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/NSSMIC.2009.5401924\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Nuclear Science Symposium conference record. Nuclear Science Symposium","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/NSSMIC.2009.5401924","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
FastSPECT III 是一种固定式单光子发射计算机断层扫描(SPECT)成像仪,专门用于啮齿类动物大脑神经病理学的成像和研究,包括阿尔茨海默氏症和帕金森氏症。20 个独立的 BazookaSPECT[1]伽马射线探测器采集球形视场的投影,并根据所需的分辨率和灵敏度选择针孔。每个 BazookaSPECT 探测器都由一个柱状 CsI(Tl)闪烁体、图像增强器、光学透镜和快帧率 CCD 相机组成。数据流通过火线接口传回处理计算机,图形处理器(GPU)的大量使用确保了每一帧数据都能得到实时处理,以提取单个伽马射线事件的图像。本文详细介绍了系统设计、成像孔径制造方法和初步投影图像。
System Integration of FastSPECT III, a Dedicated SPECT Rodent-Brain Imager Based on BazookaSPECT Detector Technology.
FastSPECT III is a stationary, single-photon emission computed tomography (SPECT) imager designed specifically for imaging and studying neurological pathologies in rodent brain, including Alzheimer's and Parkinsons's disease. Twenty independent BazookaSPECT [1] gamma-ray detectors acquire projections of a spherical field of view with pinholes selected for desired resolution and sensitivity. Each BazookaSPECT detector comprises a columnar CsI(Tl) scintillator, image-intensifier, optical lens, and fast-frame-rate CCD camera. Data stream back to processing computers via firewire interfaces, and heavy use of graphics processing units (GPUs) ensures that each frame of data is processed in real time to extract the images of individual gamma-ray events. Details of the system design, imaging aperture fabrication methods, and preliminary projection images are presented.