Lorance Wilson, Sarah Cross, James Gimzewski, JianYu Rao
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Nanocytology: a novel class of biomarkers for cancer management.
Recently, cellular mechanical properties have received increasing attention as a potential biophysical marker for cancer cells. The analysis of mechanical profiles at the single-cell level may provide information that is potentially useful to assess tumor prognosis and response to therapy. This feature review discusses a novel nanocytology approach that combines traditional morphology assessment, molecular analysis and nanomechanical analysis of cancer cells.
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