在美国,丙型肝炎相关肝硬化及其并发症的患病率预计会增加:目前的抗病毒治疗覆盖率没有影响?

S. Deuffic-Burban
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引用次数: 8

摘要

Davis等人使用多队列自然历史模型和树模型,预测了美国慢性丙型肝炎(CHC)及其并发症的未来患病率。首先,该模型预测在2010年许多患者已经进展到F4,包括失代偿性肝硬化和HCC。其次,该模型强调肝硬化及其并发症在60岁以后最为常见,与感染发生时间无关。最后,该模型显示当前的治疗模式对丙型肝炎并发症的发生率几乎没有影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Expected increase in prevalence of HCV-related cirrhosis and its complications in the United States: No effect of current antiviral treatment coverage?

Davis et al. projected the future prevalence of chronic hepatitis C (CHC) and its complications in the United States, using a multicohort natural history model with a tree model. First, the model predicted that in 2010 many patients have already progressed to F4, including to decompensanted cirrhosis and HCC. Second, the model emphasized that cirrhosis and its complications are most common after 60 years old, regardless of when the infection occurred. Finally, the model showed that current treatment patterns will have little effect on the incidence of the complications hepatitis C.

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