思瑞康是否因误用/滥用而名声不佳?

Randy A Sansone, Lori A Sansone
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引用次数: 0

摘要

奎硫平是一种非典型抗精神病药,已成为一系列案例报告的主题,这些案例报告表明奎硫平有可能被误用/滥用。现有病例表明男性占优势;口服、鼻内或静脉注射给药途径;在监狱或精神病住院环境中滥用/虐待;以及有大量滥用多种药物史的人。虽然已有可能的药理学解释,但与其他非典型抗精神病药物相比,喹硫平误用/滥用的风险较高,尚无明确的解释。同样,也没有可用的动物或人类经验研究来评估风险。在这个关键时刻,精神科和初级保健机构的临床医生只能对潜在风险保持警惕,特别是对符合当前人口统计特征的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is seroquel developing an illicit reputation for misuse/abuse?

Quetiapine, an atypical antipsychotic, has been the subject of a series of case reports that suggest a potential for misuse/abuse. The available cases indicate a male predominance; oral, intranasal, or intravenous routes of administration; misuse/abuse in jail or inpatient psychiatric settings; and subjects with extensive histories of polysubstance abuse. While possible pharmacological explanations have been proffered, compared to the other atypical antipsychotics, there is no clear explanation for an alleged higher risk of misuse/abuse with quetiapine. Likewise, there are no available animal or human empirical studies to evaluate risk. At this juncture, clinicians in psychiatric and primary care settings can only remain alert to a potential risk, particularly in patients who meet the current demographic profile.

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