Fernando Prete, Alda Montanaro, Leonardo Vincenti, Paolo Nitti, Francesco Paolo Prete
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Over the past decade 31 patients (mean age 62 years; 52.9% male) with postoperative dehiscences of the thoraco-abdominal oesophagus, stomach or duodenum underwent reintervention. During the surgical repair an IED was inserted in 17, while no IED was inserted in 14 (NOIED): the two groups were well matched for age, gender, primary pathology, site and type of leak. The overall operative mortality (30 days) was 16% (12.5% IED vs. 20% NOIED), and morbidity was 45% (37.5% IED vs. 53.3% NOIED). The rate of leak relapse was significantly different: 6% IED vs. 20% NOIED. In the last 5 years the IED procedure has also been used preventively with promising outcomes in another 16 other high-risk upper gastrointestinal suture patients. The results of this retrospective study appear to support the use of the IED procedure to minimize the risk of failure of the suture/anastomosis in upper gastrointestinal surgery. Other studies are needed to validate the efficacy of this supplementation of surgical treatment.</p>","PeriodicalId":75700,"journal":{"name":"Chirurgia italiana","volume":"61 5-6","pages":"523-9"},"PeriodicalIF":0.0000,"publicationDate":"2009-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Isoperistaltic endoluminal drainage (IED) in the surgical treatment of upper digestive tract dehiscence].\",\"authors\":\"Fernando Prete, Alda Montanaro, Leonardo Vincenti, Paolo Nitti, Francesco Paolo Prete\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Dehiscence of upper gastrointestinal sutures still remains a severe clinical problem and often requires complex surgical repair. Despite its multifactorial aetiopathogenesis, endoluminal pressure seems to play an important role in the onset and maintenance of this complication. The efficacy of isoperistaltic endoluminal drainage (IED) in the operative treatment or prevention of upper gastrointestinal surgical dehiscence was assessed in a retrospective study. The IED procedure is obtained by means of a two-way nasogastric tube inserted in the proximal jejunum through the abdominal and advanced to the site of the leak in order to achieve low endovisceral pressure, normal intestinal free flow downstream of the lesion and monitoring of the healing process. Over the past decade 31 patients (mean age 62 years; 52.9% male) with postoperative dehiscences of the thoraco-abdominal oesophagus, stomach or duodenum underwent reintervention. During the surgical repair an IED was inserted in 17, while no IED was inserted in 14 (NOIED): the two groups were well matched for age, gender, primary pathology, site and type of leak. The overall operative mortality (30 days) was 16% (12.5% IED vs. 20% NOIED), and morbidity was 45% (37.5% IED vs. 53.3% NOIED). The rate of leak relapse was significantly different: 6% IED vs. 20% NOIED. In the last 5 years the IED procedure has also been used preventively with promising outcomes in another 16 other high-risk upper gastrointestinal suture patients. The results of this retrospective study appear to support the use of the IED procedure to minimize the risk of failure of the suture/anastomosis in upper gastrointestinal surgery. 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引用次数: 0
摘要
上消化道缝合线破裂仍然是一个严重的临床问题,通常需要复杂的手术修复。尽管它是多因素的病因,但腔内压似乎在这种并发症的发生和维持中起着重要作用。回顾性评价等肠腔内引流术(IED)在手术治疗或预防上消化道手术裂孔中的疗效。IED手术是通过一根双向鼻胃管通过腹部插入空肠近端并推进到泄漏部位,以实现低内脏内压,正常肠道自由流动病变下游和监测愈合过程。在过去十年中,31例患者(平均年龄62岁;52.9%男性)术后胸腹段食管、胃或十二指肠裂开的患者接受了再介入治疗。在手术修复过程中,17例置入了IED, 14例未置入IED (NOIED):两组在年龄、性别、原发病理、部位和泄漏类型上匹配良好。总手术死亡率(30天)为16% (12.5% IED vs 20% NOIED),发病率为45% (37.5% IED vs 53.3% NOIED)。漏气复发率有显著差异:漏气复发率为6%,漏气复发率为20%。在过去的5年中,IED手术也被预防性地用于另外16例其他高风险上胃肠道缝合患者,并取得了良好的效果。这项回顾性研究的结果似乎支持使用IED手术来最大限度地减少上消化道手术中缝合/吻合失败的风险。需要其他的研究来验证这种补充手术治疗的有效性。
[Isoperistaltic endoluminal drainage (IED) in the surgical treatment of upper digestive tract dehiscence].
Dehiscence of upper gastrointestinal sutures still remains a severe clinical problem and often requires complex surgical repair. Despite its multifactorial aetiopathogenesis, endoluminal pressure seems to play an important role in the onset and maintenance of this complication. The efficacy of isoperistaltic endoluminal drainage (IED) in the operative treatment or prevention of upper gastrointestinal surgical dehiscence was assessed in a retrospective study. The IED procedure is obtained by means of a two-way nasogastric tube inserted in the proximal jejunum through the abdominal and advanced to the site of the leak in order to achieve low endovisceral pressure, normal intestinal free flow downstream of the lesion and monitoring of the healing process. Over the past decade 31 patients (mean age 62 years; 52.9% male) with postoperative dehiscences of the thoraco-abdominal oesophagus, stomach or duodenum underwent reintervention. During the surgical repair an IED was inserted in 17, while no IED was inserted in 14 (NOIED): the two groups were well matched for age, gender, primary pathology, site and type of leak. The overall operative mortality (30 days) was 16% (12.5% IED vs. 20% NOIED), and morbidity was 45% (37.5% IED vs. 53.3% NOIED). The rate of leak relapse was significantly different: 6% IED vs. 20% NOIED. In the last 5 years the IED procedure has also been used preventively with promising outcomes in another 16 other high-risk upper gastrointestinal suture patients. The results of this retrospective study appear to support the use of the IED procedure to minimize the risk of failure of the suture/anastomosis in upper gastrointestinal surgery. Other studies are needed to validate the efficacy of this supplementation of surgical treatment.