[阿比让有毒废物中毒的流行病学和临床问题]。

Sante (Montrouge, France) Pub Date : 2009-10-01 Epub Date: 2010-02-22 DOI:10.1684/san.2009.0163
Issaka Tiembre, Blaise A Koné, Kouassi Dongo, Marcel Tanner, Jakob Zinsstag, Guéladio Cissé
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引用次数: 3

摘要

未标明:2006年8月19日至21日夜间,剧毒废物被倾倒在阿比让的各个地点,向卫生当局报告了许多中毒病例,但卫生当局对这种问题毫无准备。瑞士科学研究中心的城市环境与健康研究小组及其在瑞士热带研究所的合作伙伴进行了这项研究,其目标是:描述中毒人员的流行病学概况;确定中毒的主要临床症状和危险因素;建议采取措施减轻影响,防止产生中期和长期后果。方法:本横断面研究调查了生活在排放点附近的人群(n=6)。每个地点的样本量为619人,确定1%的风险和0.4%的标准误差,因为不同地点的人为影响因素存在差异。通过样带技术在每个站点选择住户。六个小组,每个小组包括一名医生、一名公共卫生代理人和一名当地导游,在经过专门培训后收集数据。一项试点调查使最后的调查表得以证实。结果:调查对象4573人中,有毒废弃物排放期间有4344人在家,约占95%。共有2369人(51.8%)出现中毒症状。性别、居住地区和出院时是否在家都与中毒有关。按保健中心分列的中毒受害者分布情况表明,1297人(64.4%)去过AA保健中心(3/4),其中615人(约47.4%)去过公共或官方中心,778人(约60%)去过非官方中心;379人(29.2%)由非政府组织管理,159人(12.3%)由流动单位管理,63人(4.8%)由非官方公共卫生中心管理,35人(2.7%)在一个未指明的地点管理。在寻求治疗的人中,673人(约51.8%)获得了医疗处方,815人(约62.7%)直接免费获得了药物。94人(约7.2%)选择自行用药,74人(5.7%)选择传统治疗。总共有34人住院治疗,约占就医人数的2.6%。在前往保健中心的受试者中,1421人(72.8%)的病程为阳性,532人(27.7%)病程为不良。后者主诉呼吸体征,特别是咳嗽和胸痛(21.8%),消化体征(腹泻和腹胀,约21.5%),皮肤(瘙痒)和神经系统(头痛)体征(20.7%)。总的来说,在调查期间仍有532人(21.1%)出现症状。结论:本研究强调,在许多中毒患者中,症状持续超过4个月。这一现象仍在继续,虽然场址已部分清理,但对人口健康的长期影响仍然令人震惊。深入的多学科研究是探索长期影响的必要条件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Epidemiologic and clinical aspects of toxic waste poisoning in Abidjan].

Unlabelled: In the nights of 19 to 21 August, 2006, highly toxic waste products were dumped at various sites in Abidjan, and numerous cases of poisoning were reported to the health authorities, who were unprepared for such a problem. The research group on Environment and Health in Urban Environment from the Swiss Center of Scientific Research and its partners at the Swiss Tropical Institute undertook this study whose objectives were to: describe the epidemiologic profile of the people poisoned; identify the main clinical symptoms and the risk factors for poisoning; and recommend steps to attenuate the effects and to prevent intermediate- and long-term consequences.

Methodology: This cross-sectional study examined the populations living around the discharge sites (n=6). The sample size was calculated at 619 people per site, to identify a 1% risk and a standard error of 0.4%, because of variability of the human impact factor at the different sites. Households were chosen at each site by the transect technique. Six teams, each including a physician, a public health agent and a local guide collected the data, after specific training. A pilot investigation made it possible to validate the final questionnaire.

Results: Of 4573 people surveyed, 4344 people, about 95%, were home during the toxic waste discharge. In all, 2369 (51.8%) had signs of poisoning. Sex, district of residence, and presence at home at the time of the discharge were all statistically related to poisoning. The distribution of poison victims according to health centre shows that 1297 people (64.4%) visited a health center AA(3/4) 615 of them (about 47.4%) a public or official centre, and 778 (about 60%), an unofficial centre; 379 (29.2%) were managed by an NGO, 159 individuals (12.3%) by mobile units, 63 individuals (4.8%) by the unofficial public health centre, and 35 (2.7%) at an unspecified site. Of those who sought care, 673 people (about 51.8%) received a medical prescription, and 815 (or 62.7%) had been given the drug directly, for free. 94 individuals (about 7.2%) chose their own self-medication, and 74 people (5.7%) a traditional treatment. In all, 34 people, about 2.6% of those who sought care, were hospitalized. Of the subjects who went to a health centre, 1421 (72.8%) had a positive course and 532 (27.7%) an unfavourable course. The latter complained especially of respiratory signs, in particular a cough and thoracic pains (21.8%), digestive signs (diarrhoea and abdominal distension, about 21.5%), and cutaneous (pruritus) and neurological (headaches) signs (20.7%). Overall, 532 people (21.%) still presented signs during the investigation.

Conclusion: This study highlighted the persistence of the symptoms among many of those poisoned more than 4 months afterwards. This phenomenon continues, although the sites have been partially cleaned: the long-term effects on population health remain alarming. Thorough multidisciplinary studies are essential to explore the long-term effects.

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