{"title":"神经细胞是否通过分泌外泌体和微泡与内皮细胞沟通?","authors":"Neil R Smalheiser","doi":"10.1155/2009/383086","DOIUrl":null,"url":null,"abstract":"<p><p>Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.</p>","PeriodicalId":88441,"journal":{"name":"Cardiovascular psychiatry and neurology","volume":"2009 ","pages":"383086"},"PeriodicalIF":0.0000,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2009/383086","citationCount":"33","resultStr":"{\"title\":\"Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?\",\"authors\":\"Neil R Smalheiser\",\"doi\":\"10.1155/2009/383086\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.</p>\",\"PeriodicalId\":88441,\"journal\":{\"name\":\"Cardiovascular psychiatry and neurology\",\"volume\":\"2009 \",\"pages\":\"383086\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1155/2009/383086\",\"citationCount\":\"33\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cardiovascular psychiatry and neurology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2009/383086\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2009/8/3 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular psychiatry and neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2009/383086","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2009/8/3 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?
Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.
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