Richard P Baum, Cyprian Świętaszczyk, Vikas Prasad
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引用次数: 20
摘要
肺癌患者的预后主要取决于疾病的诊断阶段。对比增强CT (ceCT)和MRI在初始分期中发挥重要作用,但与正电子发射断层扫描(PET)获得的代谢或分子信息相比,形态学信息往往不足。[18] f -氟脱氧葡萄糖(FDG)是基于ATP需求增加导致肿瘤组织葡萄糖消耗增加。FDG-PET/CT已被证明在初始诊断,治疗反应评估,复发肿瘤检测,放射治疗计划以及非小细胞肺癌患者和小细胞肺癌患者的多学科管理方面具有巨大的价值。本文的目的是对FDG-PET/CT的现状进行简要的总结。
The prognosis of lung cancer patients mostly depends on the stage at which the disease is diagnosed. Contrast-enhanced CT (ceCT) and MRI play a significant role in initial staging, but often the morphological information is insufficient when compared to the metabolic or molecular information obtained by positron emission tomography (PET). [18]F-fluorine deoxyglucose (FDG) is based upon the increased demand of ATP leading to increased consumption of glucose in the tumor tissues. FDG-PET/CT has been proven to be of immense value in the initial diagnosis, evaluation of therapy reponse, detection of recurrent tumor, radiation therapy planning and in the multidisciplinary management of patients with non-small cell lung cancer as well as in patients with small cell lung cancer. The aim of this article is to present a concise summary of the present status of FDG-PET/CT.