用于RNA成像的激子控制荧光探针的合成。

Shuji Ikeda, Takeshi Kubota, Hiroyuki Yanagisawa, Mizue Yuki, Akimitsu Okamoto
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引用次数: 3

摘要

已知噻唑橙染料的激子相互作用可抑制荧光发射。我们已经开发了杂交敏感的荧光探针利用激子相互作用的两个噻唑橙染料连接到探针。在这里,我们报告了核酸酶抗性杂交敏感探针用于长期细胞内RNA成像。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synthesis of exciton-controlled fluorescent probes for RNA imaging.

The excitonic interaction of thiazole orange dyes is known to suppress fluorescence emission. We have developed hybridization-sensitive fluorescent probes utilizing the excitonic interaction of two thiazole orange dyes connected to the probes. Here, we report nuclease-resistant hybridization-sensitive probes for long-term intracellular RNA imaging.

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