[Or-Vil装置全腹腔镜经裂孔扩大全胃切除术:治疗Siewert II型和III型肿瘤的初步结果]。

Chirurgia italiana Pub Date : 2009-05-01
Luca Maria Siani, Fabrizio Ferranti, Marco Marzano, Marco Benedetti, Alberto Quintiliani
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引用次数: 0

摘要

胃-食管交界处腺癌在西方国家逐渐上升,由于其预后不良,对肿瘤外科医生提出了真正的临床挑战。我们评估了我们的初步经验,全腹腔镜经裂孔扩大全胃切除术与Or-Vil装置治疗siwert型II和III型肿瘤的胃-食管交界处。本研究共纳入10例患者;分析ASA评分、疾病分期、手术时间、估计失血量、淋巴结数量、近端切缘清扫长度、发病率和死亡率。死亡率为零,发病率为20%;近端间隙平均为5.7 cm,所有边缘均无肿瘤(RO)。淋巴结数量为38 +/- 19。未见吻合口瘘或大裂。根据我们的初步经验,全腹腔镜经裂孔扩展全胃切除术治疗胃-食管交界处的siwert II型和III型肿瘤是安全有效的,并且根据我们的初步结果,肿瘤学上是正确的,但它仍然是一个复杂的高级腹腔镜手术,需要专业技能和足够的经验。需要前瞻性随机试验(可能是多中心试验)来确定其在长期肿瘤预后方面的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Whole laparoacopic trans-hiatal extended total gastrectomy with the Or-Vil device: preliminary results in the treatment of Siewert type II and III tumors].

Adenocarcinoma of the gastro-oesophageal junction is progressively rising in western countries and, because of its poor prognosis, presents a real clinical challenge for the oncological surgeon. We evaluate our initial experience with wholly laparoscopic trans-hiatal extended total gastrectomy with the Or-Vil device for treating Siewert type II and III tumours of the gastro-oesophageal junction. Ten patients were enrolled in the present study; ASA score, stage of disease, length of surgery, estimated blood loss, number of lymph nodes harvested, length of proximal margin clearance, morbidity and mortality were analysed. Mortality was nil and morbidity 20%; the average proximal clearance margin was 5.7 cm and all margins were tumour-free (RO). The number of lymph nodes harvested was 38 +/- 19. Neither anastomotic fistulas nor major dehiscence were observed. In our initial experience, wholly laparoscopic trans-hiatal extended total gastrectomy for treating Siewert type II and III tumours of the gastro-oesophageal junction is safe, effective and, according to our preliminary results, oncologically correct, but it remains a complex, advanced laparoscopic procedure, requiring major skills and adequate experience. Prospective, randomised trials--possibly multicentric--are required to establish its efficacy in terms of long-term oncological outcomes.

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