神经调节和女性性功能:难治性排尿症状的治疗是否有额外的益处?

Michael S Ingber, Ibrahim A Ibrahim, Kim A Killinger, Ananias C Diokno, Kenneth M Peters
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引用次数: 17

摘要

介绍和假设:前瞻性评估因膀胱过动症(OAB)或膀胱疼痛综合征(PBS)接受InterStim植入术的女性,以确定神经调节是否对女性性功能(FSF)有任何影响。方法:在我们的InterStim数据库中,性活跃的女性在术前和6个月时完成了女性性功能指数(FSFI)。结果:105例女性中,54例有6个月的随访数据。其中,27人术前和随访时性生活活跃。平均(标准差(SD)) FSFI从术前的18.7(6.8)改善到术后的21.0 (6.0);然而,这没有统计学意义(p = 0.220)。OAB患者亚组分析显示,术前平均(SD) FSFI为18.6(8.0),6个月时平均(SD) FSFI为22.4 (6.4)(p = 0.257)。PBS组术前平均(SD) FSFI为18.8(6.3),6个月时平均(SD) FSFI为18.7 (5.8)(p = 0.98)。结论:神经调节不能显著改善异质人群的FSF。需要进一步的研究来证实我们的研究结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neuromodulation and female sexual function: does treatment for refractory voiding symptoms have an added benefit?

Introduction and hypothesis: Women undergoing InterStim implantation for overactive bladder (OAB) or painful bladder syndrome (PBS) were prospectively evaluated to determine if neuromodulation has any effect on female sexual function (FSF).

Methods: Sexually active women in our InterStim database completed a female sexual function index (FSFI) preoperatively and at 6 months.

Results: Of 105 women, 54 have 6-month follow-up data. Of these, 27 were sexually active preoperatively and at follow-up. The mean (standard deviation (SD)) FSFI improved from 18.7 (6.8) preoperatively to 21.0 (6.0) postoperatively; however, this was not statistically significant (p = 0.220). Subgroup analysis of patients with OAB revealed that mean (SD) FSFI preoperatively was 18.6 (8.0) and 22.4 (6.4) at 6 months (p = 0.257). In the PBS group, mean (SD) FSFI was 18.8 (6.3) preoperatively and 18.7 (5.8) at 6 months (p = 0.98).

Conclusions: Neuromodulation does not significantly improve FSF in a heterogenous population. Additional studies are needed to confirm the findings in our study.

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