儿童逆行和副咽脓肿:药物治疗失败的预测因素

R. Wagner , F. Espitalier , A. Madoz , G. Picherot , P. Bordure , O. Malard
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引用次数: 7

摘要

目的探讨无危及生命并发症的儿童咽旁脓肿术后首次药物治疗(静脉注射抗生素)失败的预测因素。患者和方法回顾性研究1998年至2006年在南特大学医院治疗的45名儿童咽旁脓肿。结果中位年龄为3.8岁。30例(66%)患者需要手术治疗。初始药物治疗失败的重要预测因素为:患者年龄小于3岁,静脉抗生素治疗前症状超过3天,白细胞计数高于每毫米立方2.2万个,低密度直径大于20毫米,CT扫描显示脓肿。既往在家抗生素治疗与药物治疗失败无显著相关。广谱抗生素治疗并没有改善医疗结果。结论强调了儿童复发性和/或咽旁脓肿初始药物治疗失败的预测因素;这些因素有助于确定临床方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Abcès rétro- et parapharyngés de l’enfant : facteurs prédictifs d’échec du traitement médical

Objective

To consider the predictive factors of failure after medical treatment (intravenous antibiotics) first initiated in children with retro- and parapharyngeal abscess, without life-threatening complications.

Patients and methods

Retrospective study between 1998 and 2006 of 45 children treated at the Nantes University Hospital for a retro- and paraphayngeal abscess.

Results

Median age was 3.8 years. Thirty (66%) patients required surgical management. Significant predictive factors of failure of initial medical therapy were: patients under 3 years of age, symptoms more than 3 days before intravenous antibiotic therapy, leukocyte count higher than 22,000 per millimeter cube, hypodensity diameter greater than 20 mm, and abscess demonstrated on CT scan. Previous antibiotic therapy at home was not significantly related to medical treatment failure. Broad-spectrum antibiotic therapy associations did not improve medical outcome.

Conclusion

The predictive factors of failure after initial medical therapy for retro- and/or parapharyngeal abscess in children are underlined; these factors help determine the clinical approach.

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