[瓦加杜古Yalgado Ouedraogo大学医院中心皮肤科45例疣状表皮发育不良的临床和流行病学特征]。

Dakar medical Pub Date : 2007-01-01
Traoré F Barro, A Traoré, Lompo O Goumbri, L Ilboudo, A M Bassole, P Niamba, B R Soudre, E Heid, E Grosshans
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引用次数: 0

摘要

简介:疣状表皮发育不良是一种罕见的常染色体隐性遗传性皮肤病,其特征是慢性弥散性皮肤感染人乳头瘤病毒。这些患者大多有遗传性或获得性免疫缺陷。患者与方法:回顾性分析1992年1月1日至2005年6月30日在我院皮肤科收治的疣状表皮发育不良患者13年零6个月的临床资料。结果:收集疣状表皮发育不良45例。年龄3 ~ 57岁,平均24.6岁。最受关注的年龄段是0到9岁。其中女性29人(64.4%),男性16人(35.6%)。发病表现为2 ~ 3mm大小的丘疹,伴大小相同的浅色细鳞状斑点。我们注意到三个瘙痒病例。我们发现37.7%的家庭病例。我们观察到14例HIV阳性患者和1例癌症患者。结论:本研究证实疣状表皮发育不良是罕见的。遗传因素或免疫缺陷会支持这种疾病的出现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Epidermodysplasia verruciformis: clinicaland epidemiological features of 45 cases in the Department of Dermatology at the University Hospital Center of Yalgado Ouedraogo, Ouagadougou].

Introduction: The epidermodysplasia verruciformis is a rare, autosomic, recessive, genodermatose characterized by a chronic, disseminated, cutaneous infection with human papillomavirus. The majority of these patients have a genetic or acquired immunodeficiency.

Patients and methods: This retrospective study was conducted on the records of all patients who presented in our dermatology department with an epidermodysplasia verruciformis in a 13 years and 6 months period, from January 1st, 1992 to June 30th, 2005.

Results: We have collected 45 cases of epidermodysplasia verruciformis. They were aged from 3 to 57 years, with a mean of 24.6 years. The most concerned age bracket was that from zero to 9 years. They were 29 women (64.4%) and 16 men (35.6%). The eruption presented as papules of 2 to 3 mm size, associated with hypochromic, finely squamous macules with the same size. We noted three cases of itching. We found 37.7% of family cases. We observed 14 cases of HIV positive patients and one case of cancer.

Conclusion: This study confirmed that the epidermodysplasia verruciformis was rare. Genetic factors or immunodeficiency would support the appearance of the disease.

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