手性分离的筛选方法。

4区 化学 Q4 Chemistry
Debby Mangelings, Yvan Vander Heyden
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引用次数: 12

摘要

本文综述了近十年来在手性分离领域中开发的通用筛选方法或分离策略。这个想法是给不同的技术的概述,随着执行手性分离应用这些技术的可能性。考虑定义了通用条件的研究论文,即适用于结构多样的大集合物质,无论是作为筛选实验,还是作为筛选步骤后包含一些优化可能性的策略。这应该允许读者了解在手性分离领域中使用的技术,这些技术可以进行一般分析,并且可以考虑作为手性方法开发的第一步的条件。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening approaches for chiral separations.

The publications of the past 10 years in which generic screening approaches or separation strategies were developed in the field of chiral separations are reviewed. The idea is to give an overview of the different techniques that were used along with the possibilities of performing chiral separations applying these techniques. Research papers in which generic conditions are defined, that is, applicable on large sets of structurally diverse substances, either as a screening experiment or as a strategy including some optimization possibilities after the screening step, were considered. This should allow giving the reader an idea about the techniques used in the chiral separation field that enable generic analysis and about the conditions that can be considered as a first step in chiral method development.

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来源期刊
Advances in Chromatography
Advances in Chromatography CHEMISTRY, ANALYTICAL-
CiteScore
1.40
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