实验性左原位单肺移植猪模型。

IF 0.8
Mădălina Grigoroiu, C Scarlat, C Stănescu, Roxana Apriotesei, G Merlusca, Andra Popescu, B Trifan
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引用次数: 0

摘要

未标记:猪模型是移植实验中常用的一种原位肺移植模型。本研究的目的是在猪模型上控制移植技术,并执行该过程的学习曲线,尽可能多地从手术而不是麻醉的角度来看。方法:对20对体重30 ~ 35 kg的家养猪进行原位左肺移植手术20例。记录气管插管时间、监测时间、支气管、动脉、静脉吻合时间、热缺血时间。并对发病和死亡原因进行了分析。结果:支气管吻合为褥垫式吻合。所有支气管吻合口均密闭。动脉吻合术为流动褥垫端对端吻合术。静脉回流采用左心房-静脉流动褥垫缝合吻合术。所有动脉、静脉吻合口血流均满意。结论:建立了猪肺移植实验模型。麻醉和外科小组完成了他们的学习曲线。各种吻合次数,缩短了手术总时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Experimental left orthotopic mono-pulmonary transplantation swine model].

Unlabelled: The swine model is an orthotopic pulmonary transplantation model often uses in the transplantation experiments. The purpose of this study is to control the transplantation technique on swine model and perform the learning curve of this procedure, as much from surgical than anaesthetic point of view.

Methods: 20 orthotopic left pulmonary transplantations were performed on 20 pairs of domestic female pigs, weighting 30-35 kg. Tracheal intubation's time, monitoring time, bronchial, arterial and venous anastomosis time, warm ischemia time, were recorded. The causes of morbidity and mortality were also analyzed.

Results: Bronchial anastomosis was a running mattress suture. All bronchial anastomoses were airtight. Arterial anastomosis was a running mattress end-to-end anastomosis. The venous return was carried out by a left atrium-venous running mattress suture anastomosis. Satisfied blood flows in all arterial and venous anastomoses were obtained.

Conclusions: We established an experimental swine model of pulmonary transplantation. The anaesthetic and surgical team performed their learning curve. Various anastomoses times and consequently, the total time of the intervention, were shortened.

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