利用EST数据检测差异表达基因的经验贝叶斯方法。

Na You, Junmei Liu, Chang Xuan Mao
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引用次数: 2

摘要

从表达序列标签(est)数据中检测差异表达基因已受到广泛关注。介绍了一种经验贝叶斯方法,其中估计基因表达模式并用于定义检测统计。根据检测统计数据,可以宣布显著差异表达的基因。通过仿真验证了所提方法的性能。研究了两个实际应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

An empirical bayesian method for detecting differentially expressed genes using EST data.

An empirical bayesian method for detecting differentially expressed genes using EST data.

An empirical bayesian method for detecting differentially expressed genes using EST data.

Detection of differentially expressed genes from expressed sequence tags (ESTs) data has received much attention. An empirical Bayesian method is introduced in which gene expression patterns are estimated and used to define detection statistics. Significantly differentially expressed genes can be declared given detection statistics. Simulation is done to evaluate the performance of proposed method. Two real applications are studied.

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