{"title":"小鼠固有层嗅神经轴突直径的年龄相关性变化。","authors":"Kenta Watanabe, Kenji Kondo, Tatsuya Yamasoba, Kimitaka Kaga","doi":"10.1080/03655230701597598","DOIUrl":null,"url":null,"abstract":"<p><strong>Conclusion: </strong>The present study demonstrated the age-related decrease in the axonal diameter of the olfactory nerve. This finding may represent the maturational change of the olfactory receptor neurons.</p><p><strong>Objectives: </strong>The aim of this study was to investigate age-related changes in the axonal diameter of the olfactory nerve in the lamina propria.</p><p><strong>Materials and methods: </strong>Female ICR mice, postnatal age 10 days, 3 months, 7 months, and 16 months, were studied. The electron micrographs of septal olfactory mucosa were used to measure the axonal diameters of olfactory nerves.</p><p><strong>Results: </strong>The distribution of the diameter shifted toward the thinner side between 10-day-old and 3-month-old mice. The axonal diameter showed significant decreases (p < 0.001) from the age of 10 days to that of 3 months.</p>","PeriodicalId":7027,"journal":{"name":"Acta oto-laryngologica. Supplementum","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/03655230701597598","citationCount":"4","resultStr":"{\"title\":\"Age-related change in the axonal diameter of the olfactory nerve in mouse lamina propria.\",\"authors\":\"Kenta Watanabe, Kenji Kondo, Tatsuya Yamasoba, Kimitaka Kaga\",\"doi\":\"10.1080/03655230701597598\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Conclusion: </strong>The present study demonstrated the age-related decrease in the axonal diameter of the olfactory nerve. This finding may represent the maturational change of the olfactory receptor neurons.</p><p><strong>Objectives: </strong>The aim of this study was to investigate age-related changes in the axonal diameter of the olfactory nerve in the lamina propria.</p><p><strong>Materials and methods: </strong>Female ICR mice, postnatal age 10 days, 3 months, 7 months, and 16 months, were studied. The electron micrographs of septal olfactory mucosa were used to measure the axonal diameters of olfactory nerves.</p><p><strong>Results: </strong>The distribution of the diameter shifted toward the thinner side between 10-day-old and 3-month-old mice. The axonal diameter showed significant decreases (p < 0.001) from the age of 10 days to that of 3 months.</p>\",\"PeriodicalId\":7027,\"journal\":{\"name\":\"Acta oto-laryngologica. Supplementum\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2007-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/03655230701597598\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta oto-laryngologica. Supplementum\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/03655230701597598\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta oto-laryngologica. Supplementum","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/03655230701597598","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Age-related change in the axonal diameter of the olfactory nerve in mouse lamina propria.
Conclusion: The present study demonstrated the age-related decrease in the axonal diameter of the olfactory nerve. This finding may represent the maturational change of the olfactory receptor neurons.
Objectives: The aim of this study was to investigate age-related changes in the axonal diameter of the olfactory nerve in the lamina propria.
Materials and methods: Female ICR mice, postnatal age 10 days, 3 months, 7 months, and 16 months, were studied. The electron micrographs of septal olfactory mucosa were used to measure the axonal diameters of olfactory nerves.
Results: The distribution of the diameter shifted toward the thinner side between 10-day-old and 3-month-old mice. The axonal diameter showed significant decreases (p < 0.001) from the age of 10 days to that of 3 months.
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