儿童胰腺实性囊状乳头状瘤8例。

Ke-Ren Zhang, Hui-Min Jia, Hong Shu, Xin-Yuan Li
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引用次数: 0

摘要

目的:探讨儿童胰腺实性囊性乳头状瘤(SCPT)的临床病理特点。方法:对2000 ~ 2005年8例胰腺SCPT进行回顾性分析。除一例外,所有病例均为女性。平均年龄为12.8岁。通过病例回顾,我们讨论了儿童SCPT的临床和病理特征。结果:主诉为腹痛及可触及肿块。其中头部3例,身体1例,胰腺尾部4例。手术包括局部切除(1例)、远端胰腺切除术(5例)、胰十二指肠切除术(1例)和活检(1例)。组织学检查显示实性伴囊性区及乳头状突起8例;免疫组化检查α -抗胰蛋白酶(AACT)阳性率100%,vinmentin阳性率87.5%,神经元特异性烯醇化酶(NSE)阳性率62.5%。术后随访2个月~ 4年,1例术后丢失,全部存活。2例SCPT复发。结论:SCPT主要发生在年轻女性,通常可以通过手术切除治愈,预后良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Solid cystic papillary tumor of pancreas in eight children.

Objective: To estimate the clinical and pathological features of pancreatic solid cystic papillary tumor (SCPT) in children.

Methods: From 2000 to 2005, 8 cases with SCPT of the pancreas were analyzed retrospectively. All cases but one were females. Average age was 12.8 years. By case review, we discussed the clinical and pathological features of SCPT in children.

Results: The chief complains were abdominal pain and palpable mass. There were 3 cases in the head, 1 case in the body, and 4 cases in the tail of pancreas. The procedures employed included local resection (1 case), distal pancreatectomy (5 cases), pancreaticoduodenectomy (1 case), and biopsy (1 case). Histological examination showed solid with cystic areas and papillary protrusions in the 8 cases; as for immunohistochemical examinations, the positive rate was 100% for alpha-antitrypsin (AACT), 87.5% for vinmentin, and 62.5% for neuron-specific enolase (NSE). The patients were followed up for 2 months to 4 years but one was lost by follow-up and all were alive postoperatively. SCPT in 2 cases relapsed.

Conclusion: Occurring predominantly in young females, SCPT is usually curable by surgical resection with a favorable prognosis.

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