Yuru Li, Delong Liu, Yuanyuan Zhang, Ping Wang, Baodong Du
{"title":"老年大鼠耳蜗BDNF和trk B的表达。","authors":"Yuru Li, Delong Liu, Yuanyuan Zhang, Ping Wang, Baodong Du","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.</p><p><strong>Method: </strong>The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.</p><p><strong>Result: </strong>The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.</p><p><strong>Conclusion: </strong>The expression of BDNF is closely correlated to presbycusis in the aged rats.</p>","PeriodicalId":79680,"journal":{"name":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","volume":"20 19","pages":"894-5"},"PeriodicalIF":0.0000,"publicationDate":"2006-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Expression of BDNF and trk B in the cochleas of the aged rats].\",\"authors\":\"Yuru Li, Delong Liu, Yuanyuan Zhang, Ping Wang, Baodong Du\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.</p><p><strong>Method: </strong>The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.</p><p><strong>Result: </strong>The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.</p><p><strong>Conclusion: </strong>The expression of BDNF is closely correlated to presbycusis in the aged rats.</p>\",\"PeriodicalId\":79680,\"journal\":{\"name\":\"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology\",\"volume\":\"20 19\",\"pages\":\"894-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Expression of BDNF and trk B in the cochleas of the aged rats].
Objective: To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.
Method: The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.
Result: The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.
Conclusion: The expression of BDNF is closely correlated to presbycusis in the aged rats.
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