[急性髓性白血病患者颅内粒细胞肉瘤]。

No to shinkei = Brain and nerve Pub Date : 2006-09-01
Harue Obara, Shinjitsu Nishimura, Nakamasa Hayashi, Yoshihiro Numagami, Tomoo Inoue, Kohmei Kubo, Mitsuomi Kaimori, Michiharu Nishijima
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引用次数: 0

摘要

粒细胞肉瘤(GS)是由未成熟的白血病细胞组成的髓外肿瘤。GS通常表现为血液肿瘤病程中的并发症,如急性髓母细胞白血病以及骨髓增生性和骨髓增生异常综合征。根据肿瘤肿块的绿色,该肿瘤也被称为色素瘤。GS的中枢神经系统表现极为罕见。我们报告一个41岁的男性急性白血病M7型,谁在完全缓解后发展GS在右侧枕叶。手术发现硬瘤呈绿色,提示为色肌瘤。组织学表现为GS型肿瘤。报告的急性髓系白血病GS多为M2 FAB型,并有染色体易位。本例患者为M7 FAB型,无特异性染色体易位。在AML: M7患者中,GS的发生极为罕见。这是首例AML: M7伴中枢神经系统GS的病例报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Intracranial granulocytic sarcoma in a patient with acute myeloid leukemia].

Granulocytic sarcoma (GS) is extramedullary tumor composed of immature leukemic cells. GS is presenting usually as a complication during the course of hematologic neoplasm, such as acute myeloblastic leukemia as well as myeloproliferative and myelodysplastic syndrome. The tumor was also called chroloma based on the green color of the tumorous mass. Central nervous system manifestations of GS are extremely rare. We report a 41-year-old man with acute leukemia type M7, who developed GS in the right occipital lobe after complete remission was achieved. Operative findings revealed the color of the hard tumor was greenish, which suggested the tumor was chroloma. Histological findings showed the tumor was GS. The majority of reported cases of GS in acute myeloid leukemia were M2 FAB classification and have chromosome translocation. Our patient was M7 FAB classification, not have specific chromosome translocation. GS occurrence in AML: M7 patient was extremely rare. This is the first case report of AML: M7 with GS in the central nervous system.

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