[阻塞性睡眠呼吸暂停的外科治疗]。

P Kessler, F Ruberg, H Obbarius, H Iro, F W Neukam
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引用次数: 4

摘要

梗阻性睡眠呼吸暂停(OSA)是一种常见的成人疾病,但它也发生在严重下颌发育不全的新生儿中。阻塞性睡眠呼吸暂停的临床意义是由于上气道塌陷引起的低氧血症和睡眠破碎。近年来,阻塞性睡眠呼吸暂停因其对心功能的潜在严重影响而受到广泛关注。除了白天的困倦和疲劳外,中风和心力衰竭的风险更高,预期寿命也会大大缩短。本文回顾了常见的外科手术,重点是下颌推进手术。材料和方法:6例成人(平均年龄46,9岁;2名女性,4名男性;BMI平均为28kg/m(2)),患有OSA且有长期不成功的持续气道正压(CPAP)治疗史,进行双颌推进。术前应用多导睡眠图评估呼吸障碍;根据“爱普沃斯嗜睡量表”记录白天的嗜睡情况。对照组在治疗后6个月进行。所有患者均有规律的上颌间关系。根据颅颌面矫正外科的原则计划和实施双颌前进。为了扩大后气道空间,我们主要关注下颌骨前移10mm。结果:呼吸暂停/低通气指数由术前37/h降至治疗后4/h。最小外周血氧饱和度从78%上升到89%,平均血氧饱和度从92%上升到95%。唤醒指数由24/h降至9/h。打鼾的时间从29.5%减少到6.9%。根据“爱普沃斯嗜睡量表”,患者的评分从11分提高到4分。睡眠有恢复体力的作用。所有的手术过程都很顺利。结论:cpap治疗是OSA的标准治疗方法。然而,在一些患者中,cpap治疗不能应用,失败或不被很好地接受。各种各样的外科手术治疗阻塞性睡眠呼吸暂停已被描述。成人双颌推进和新生儿骨牵张术是安全且成功的手术技术,可立即改善OSA。骨牵张治疗可避免新生儿气管切开术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Surgical management of obstructive sleep apnea].

Introduction: Obstructive sleep apnea (OSA) is a common disorder in adults, however it also occurs in neonates with severe mandibular hypoplasia. The clinical significance of OSA results from hypoxemia and sleep fragmentation due to a collapse of the upper airway. Recently OSA has received much attention due to its potentially serious consequences on cardiac function. Besides daytime sleepiness and fatigue life expectancy is significantly shortened by a higher risk for apoplectic insults and heart failures. This paper reviews common surgical procedures with an emphasis on jaw advancement procedures.

Material and methods: In six adults (mean age 46,9 ys; 2 female, 4 male; BMI averaged 28kg/m(2)) suffering from OSA with a history of a long-lasting unsuccessful continuous positive airway pressure (CPAP) therapy a bimaxillary advancement was performed. The respiratory disturbance was preoperatively evaluated by polysomnography; daytime sleepiness was recorded according to the 'Epworth Sleepiness Scale'. Controls were performed six months after therapy. All patients had a regular intermaxillary relation. Bimaxillary advancement was planned and performed according to the principles of cranio-maxillofacial corrective surgery. To widen the posterior airway space much attention was focused on the advancement of the mandible by 10mm.

Results: The apnea/hypopnea index decreased from preoperatively 37/h to 4/h after treatment. The minimal peripheral oxygen saturation increased from 78% to 89%, whereas the average oxygen saturation raised from 92 to 95%. The arousal index decreased from 24/h to 9/h. Periods of snoring were reduced from 29,5% to 6,9%. According to the 'Epworth Sleepiness Scale' the patients' estimation improved from a level of 11 to 4. Sleep had a recuperating effect. All surgical procedures were uneventful.

Conclusion: Standard treatment of OSA is the CPAP-therapy. In some patients, however, CPAP-therapy cannot be applied, fails or is not well accepted. A great variety of surgical procedures for the treatment of OSA have been described. Bimaxillary advancement in adults and osteodistraction in neonates are safe and successful surgical techniques for an immediate improvement in OSA. Osteodistraction treatment can help to avoid tracheotomy in neonates.

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