CNS lymphoma in an AIDS patient involving the posterior fornix case report.

We report an unusual presentation of CNS lymphoma involving the posterior fornix in a patient with AIDS. The patient's initial symptoms included progressive cognitive impairment, consistent with AIDS dementia, as well as impotence and urinary retention suggestive of myelopathy. An MR scan with gadolinium-DTPA enhancement demonstrated enhancing lesions in the cerebellum and in the posterior fornix. At autopsy, the later lesions proved to be lymphoma. This case demonstrates the unusual clinical features that may occur with lesions in the limbic system and importance of gadolinium-enhanced MRI in the evaluation of symptoms of cognitive impairment in patients with advanced HIV infection.