低血糖指数食物应该在改善1型和2型糖尿病患者的总体血糖控制方面发挥作用,更具体地说,在纠正餐后过度高血糖方面发挥作用。

Gérard Slama, Fabienne Elgrably, Morvarid Kabir, Salwa Rizkalla
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引用次数: 10

摘要

大量证据表明,在糖尿病和/或高脂血症患者以及受代谢综合征影响的受试者中,使用低血糖指数(GI)食物对改善代谢紊乱有非常显著的影响。对这一概念提出令人信服的证据的研究即使有,也是非常罕见的。改善不仅在餐后血糖和胰岛素变化,而且在循环血浆脂质水平和脂肪细胞的形态和功能。在糖尿病患者的饮食咨询中使用低GI食物的概念并不排斥其他改善餐后和整体血糖控制的措施。相反,使用低GI食物应被视为改善糖尿病控制的其他手段和工具之一(如其他饮食调整,使用改变餐后血糖的特异性和非特异性药物治疗)。在这些疗法中,最有希望的是α -葡萄糖苷酶抑制剂、格列尼德、快速胰岛素类似物以及不久的将来GLP1类似物。同样,所有这些类型的药物可以相互关联,以获得不低于20和不高于40-50 mg/dl血糖的餐后delta偏移目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Low glycemic index foods should play a role in improving overall glycemic control in type-1 and type-2 diabetic patients and, more specifically, in correcting excessive postprandial hyperglycemia.

There is a large bulk of evidence that using low glycemic index (GI) foods has a very significant impact on the amelioration of metabolic disturbances observed in diabetic and/or hyperlipidemic patients and in subjects affected by the metabolic syndrome. Studies bringing convincing evidence against this concept are very rare if any. Improvement is observed not only in postprandial blood glucose and insulin variations but also in circulating plasma lipid levels and the morphology and function of adipocytes. Using the concept of low GI foods in diet counseling of diabetic patients is not exclusive of other measures to improve postprandial and overall blood glucose control. On the contrary, the use of low GI foods should be considered as one of other means and tools available to improve diabetes control (such as other dietary modifications, use of specific and nonspecific drug therapy altering postprandial blood glucose). Among these therapies, the most promising ones are alpha-glucosidase inhibitors, glynides, rapid insulin analogues and in the near future the GLP1 analogue. Again, all these classes of drugs could be associated with one another in order to obtain a postprandial delta excursion target of not below 20 and not above 40-50 mg/dl blood glucose.

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