流感病毒抑制剂可用于流感病毒感染的化疗和/或化学预防。

E De Clercq
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引用次数: 0

摘要

目前,只有三(类)化合物可以考虑用于流感病毒感染的化疗和预防:利巴韦林、金刚烷胺/金刚乙胺和神经氨酸酶抑制剂扎那米韦和奥司他韦。后者,也以注册名称达菲(Tamiflu)为人所知,似乎是最适合的,因为它对甲型和乙型流感病毒感染有效,并且可以方便地以胶囊形式口服(每天两次)。在潜在的甲型流感病毒大流行之后,最好手头有足够数量的奥司他韦,以应对这种新出现的感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Influenza virus inhibitors available for the chemotherapy and/or chemoprophylaxis of influenza virus infections.

There are, at present, only three (classes of) compounds that could be considered for the chemotherapy and -prophylaxis of influenza virus infections: ribavirin, amantadine/rimantadine and the neuraminidase inhibitors zanamivir and oseltamivir. The latter, also known under the registered name of Tamiflu, seems to be the most indicated, as it is effective against influenza A and B virus infections and can be conveniently administered orally in capsule form (twice daily). In the wake of a potential influenza A virus pandemic it may be advisable to have at hand sufficient amounts of oseltamivir to affront such emerging infection.

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