{"title":"流感病毒抑制剂可用于流感病毒感染的化疗和/或化学预防。","authors":"E De Clercq","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>There are, at present, only three (classes of) compounds that could be considered for the chemotherapy and -prophylaxis of influenza virus infections: ribavirin, amantadine/rimantadine and the neuraminidase inhibitors zanamivir and oseltamivir. The latter, also known under the registered name of Tamiflu, seems to be the most indicated, as it is effective against influenza A and B virus infections and can be conveniently administered orally in capsule form (twice daily). In the wake of a potential influenza A virus pandemic it may be advisable to have at hand sufficient amounts of oseltamivir to affront such emerging infection.</p>","PeriodicalId":76790,"journal":{"name":"Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie","volume":"68 2","pages":"121-37"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Influenza virus inhibitors available for the chemotherapy and/or chemoprophylaxis of influenza virus infections.\",\"authors\":\"E De Clercq\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>There are, at present, only three (classes of) compounds that could be considered for the chemotherapy and -prophylaxis of influenza virus infections: ribavirin, amantadine/rimantadine and the neuraminidase inhibitors zanamivir and oseltamivir. The latter, also known under the registered name of Tamiflu, seems to be the most indicated, as it is effective against influenza A and B virus infections and can be conveniently administered orally in capsule form (twice daily). In the wake of a potential influenza A virus pandemic it may be advisable to have at hand sufficient amounts of oseltamivir to affront such emerging infection.</p>\",\"PeriodicalId\":76790,\"journal\":{\"name\":\"Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie\",\"volume\":\"68 2\",\"pages\":\"121-37\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2006-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Influenza virus inhibitors available for the chemotherapy and/or chemoprophylaxis of influenza virus infections.
There are, at present, only three (classes of) compounds that could be considered for the chemotherapy and -prophylaxis of influenza virus infections: ribavirin, amantadine/rimantadine and the neuraminidase inhibitors zanamivir and oseltamivir. The latter, also known under the registered name of Tamiflu, seems to be the most indicated, as it is effective against influenza A and B virus infections and can be conveniently administered orally in capsule form (twice daily). In the wake of a potential influenza A virus pandemic it may be advisable to have at hand sufficient amounts of oseltamivir to affront such emerging infection.