【结直肠癌肝转移手术治疗的外周中心体会】。

S Consolo, M Benedetti, A De Carlo, A Forti, M Marzano, L Mazzola, M Massimiani, F G Biondo, R Macarone Palmieri
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引用次数: 0

摘要

手术切除仍然是可切除的结肠直肠癌转移到肝脏患者的第一治疗选择。射频能量的应用已用于不符合可切除性标准的患者,但基于仅存在肝脏疾病的肝脏定向手术的候选人。在过去的二三十年中,肝切除术从80年代早期死亡率高达20%的手术发展到后来肝切除术患者的死亡率通常低于5%。发病率和死亡率的改善是多因素的;尽管肝手术的安全性有所提高,但肝切除术仍然是一项复杂的外科手术,具有严重的潜在发病率。本文介绍了在中等容量中心(4年内15例)对转移到肝脏的结直肠癌进行肝脏切除和/或射频消融的经验。转移性疾病的一些特征,包括转移的数量、大小和位置被确定。围手术期死亡率为0,非手术并发症发生率为40%。在这个系列中,报告的总1年生存率为80%,2年生存率为67%。本文综述了确定肝手术相关发病率和死亡率的经验因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Experience of a peripheral center in the surgical treatment of hepatic metastasis from colorectal cancer].

Surgical resection is still the first therapeutic option in patients with resectable colorectal cancer metastatic to the liver. Application of radiofrequency energy has been used in patients who did not meet the criteria for resectability and yet were candidates for a liver-directed procedure based upon the presence of liver-only disease. Hepatic resection has evolved in the last two or three decades from a procedure with associated mortality rate of up to 20% in the early 80s to usually less than 5% in patients undergoing liver resection thereafter. This improvement in morbidity and mortality is multifactorial; despite the increased safety of liver operations, hepatic resection still remains a complex surgical procedure with serious potential morbidity. The experience with liver resections and/or radiofrequency ablations, for colorectal cancer metastatic to the liver, performed at a medium-volume center (15 cases in 4 years) is presented. Some features of the metastatic disease, including the number, size and location of metastases are identified. The perioperative mortality is 0, morbidity for non surgical complications is 40%. In this series the reported overall 1-yr survival is 80%, 2-yr is 67%. This paper reviews the experienced factors that have defined the morbidity and mortality associated with liver surgery.

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