非洲爪蟾视网膜甘氨酸受体的免疫细胞化学研究。

Anatomy and Embryology Pub Date : 2006-06-01 Epub Date: 2006-01-17 DOI:10.1007/s00429-005-0076-7
Lily Vitanova
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引用次数: 7

摘要

用免疫细胞化学方法研究了非洲爪蟾视网膜中甘氨酸受体的表达。甘氨酸受体(GlyRs)通过几种不同的抗体显示,主要分布于内层(IPL)和外层丛状层。测定其组成包括alpha2和alpha3亚基。针对不同GlyRs亚基的抗体在IPL中观察到典型的点状外观和特异性层压。提出了甘氨酸受体多样性的概念,认为α 2和α 3亚基位于甘氨酸突触的不同亚型中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immunocytochemical study of glycine receptors in the retina of the frog Xenopus laevis.

The expression of glycine receptors in the retina of clawed frog, Xenopus laevis was studied immunocytochemically. Glycine receptors (GlyRs), as revealed by means of several different antibodies, were mainly distributed in the inner (IPL) and the outer plexiform layers. Their composition was determined to include alpha2 and alpha3 subunits. Typical punctate appearance and specific lamination in the IPL were seen with each of the antibodies directed against the different GlyRs' subunits. A notion for diversity of the glycine receptors was put forward, according to which the alpha2 and alpha3 subunits are located in different subtypes of glycine synapses.

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