生活质量作为酒精中毒治疗研究的结果衡量标准。

Dennis Donovan, Margaret E Mattson, Ron A Cisler, Richard Longabaugh, Allen Zweben
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引用次数: 218

摘要

目的:本文综述了迄今为止有关生活质量(QoL)与饮酒行为、酒精使用障碍和治疗结果之间关系的文献。方法:使用术语“生活质量”来描述被诊断为酒精使用障碍或正在接受酒精使用障碍治疗的个体的状态或结果结构,或使用一种或多种被认为反映患者生活质量的工具的文章,主要通过心理学摘要、MEDLINE和国家酒精滥用和酒精中毒研究所的ETOH档案数据库进行识别。结果:1993年至2004年间发表的36项研究符合这些标准。采用了12种不同的生活质量测量方法。频繁大量饮酒或间歇性大量饮酒(例如,每次饮酒五次或更多)模式与生活质量降低有关。与一般人群标准或其他慢性健康状况相比,酗酒者的生活质量水平较低。这种关系似乎受到一些社会人口学和客户特征的影响,如年龄、教育程度、性别和同时发生的精神疾病。酒精依赖者在治疗期间以及短期和长期戒酒后的生活质量都有所改善。尽管有这些改善,许多酗酒者的生活质量不太可能等于或超过正常群体。此外,在危险和有害的饮酒者中,即使没有完全戒酒,也能显著减少饮酒量并保持这种状态,这与生活质量的显著提高有关。结论:生活质量是评估酒精使用障碍个体和评估酒精中毒治疗结果时需要考虑的一个重要领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quality of life as an outcome measure in alcoholism treatment research.

Objective: The present article reviews the literature to date dealing with quality of life (QoL) as it relates to drinking behavior, alcohol use disorders and treatment outcome.

Method: Articles using the term "quality of life" to describe a status or outcome construct for individuals diagnosed with or being treated for alcohol use disorders or that used one or more instruments considered to reflect patients' QoL were identified primarily through Psychological Abstracts, MEDLINE and the National Institute on Alcohol Abuse and Alcoholism's ETOH archival database.

Results: Thirty-six studies, published between 1993 and 2004, met these criteria. Twelve different QoL measures were used. Frequent heavy drinking or episodic heavy drinking (e.g., five or more drinks per occasion) patterns were associated with reduced QoL. Alcoholics had lower levels of QoL compared with general population norms or with other chronic health conditions. This relationship appears to be moderated by a number of sociodemographic and client characteristics, such as age, education, gender and co-occurring psychiatric disorders. Alcohol-dependent individuals experience improvements in QoL across treatment and with both short-term and long-term abstinence. Despite these improvements, many alcoholic individuals' QoL is unlikely to equal or exceed that of normative groups. Also, among hazardous and harmful drinkers, achieving and maintaining a marked reduction in drinking, even without complete abstinence, is associated with significant increases in QoL.

Conclusions: QoL represents an important area to consider in assessing individuals with alcohol use disorders and in evaluating alcoholism treatment outcome.

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