广义接收机工作特性曲线下的面积。

IF 1.2 4区 数学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Pablo Martínez-Camblor, Sonia Pérez-Fernández, Susana Díaz-Coto
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引用次数: 10

摘要

受试者工作特征(ROC)曲线是一种众所周知的图形工具,通常用于评估连续标记的区分能力,指的是二元特征。曲线下面积(AUC)被提出作为一种汇总精度指标。标记值越高,通常具有所研究特征的概率越高。然而,在其他情况下,较高和较低的分数都与积极的结果相关。广义ROC (gROC)曲线被提出作为ROC曲线的适当扩展来拟合这些情况。当然,也引入了gROC曲线下相应的面积gac作为分类能力的全局度量。本文对gac的性质进行了深入的研究。给出了其经验估计量的弱收敛性,并给出了渐近方差的显式表达式。我们还得到了相关gac的渐近协方差表达式,并提出了一种非参数方法来比较它们。通过蒙特卡罗模拟研究了不同情况下的有限样本行为,并给出了一个现实世界的问题,以说明其实际应用。实现程序的R代码函数作为补充资料提供。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The area under the generalized receiver-operating characteristic curve.

The receiver operating-characteristic (ROC) curve is a well-known graphical tool routinely used for evaluating the discriminatory ability of continuous markers, referring to a binary characteristic. The area under the curve (AUC) has been proposed as a summarized accuracy index. Higher values of the marker are usually associated with higher probabilities of having the characteristic under study. However, there are other situations where both, higher and lower marker scores, are associated with a positive result. The generalized ROC (gROC) curve has been proposed as a proper extension of the ROC curve to fit these situations. Of course, the corresponding area under the gROC curve, gAUC, has also been introduced as a global measure of the classification capacity. In this paper, we study in deep the gAUC properties. The weak convergence of its empirical estimator is provided while deriving an explicit and useful expression for the asymptotic variance. We also obtain the expression for the asymptotic covariance of related gAUCs and propose a non-parametric procedure to compare them. The finite-samples behavior is studied through Monte Carlo simulations under different scenarios, presenting a real-world problem in order to illustrate its practical application. The R code functions implementing the procedures are provided as Supplementary Material.

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来源期刊
International Journal of Biostatistics
International Journal of Biostatistics MATHEMATICAL & COMPUTATIONAL BIOLOGY-STATISTICS & PROBABILITY
CiteScore
2.10
自引率
8.30%
发文量
28
审稿时长
>12 weeks
期刊介绍: The International Journal of Biostatistics (IJB) seeks to publish new biostatistical models and methods, new statistical theory, as well as original applications of statistical methods, for important practical problems arising from the biological, medical, public health, and agricultural sciences with an emphasis on semiparametric methods. Given many alternatives to publish exist within biostatistics, IJB offers a place to publish for research in biostatistics focusing on modern methods, often based on machine-learning and other data-adaptive methodologies, as well as providing a unique reading experience that compels the author to be explicit about the statistical inference problem addressed by the paper. IJB is intended that the journal cover the entire range of biostatistics, from theoretical advances to relevant and sensible translations of a practical problem into a statistical framework. Electronic publication also allows for data and software code to be appended, and opens the door for reproducible research allowing readers to easily replicate analyses described in a paper. Both original research and review articles will be warmly received, as will articles applying sound statistical methods to practical problems.
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