老年人中致命的COVID-19：先天免疫记忆帮助最需要帮助的人。

Med (New York, N.y.) Pub Date : 2021-04-09 Epub Date: 2021-02-24 DOI:10.1016/j.medj.2021.02.004

Yahya Sohrabi, Holger Reinecke, Leo A B Joosten, Mihai G Netea

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引用次数: 0

摘要

年龄是与SARS-CoV-2引起的症状严重程度相关的关键危险因素，迫切需要降低老年人的COVID-19发病率和死亡率。我们讨论的证据表明，通过卡介苗接种引起的训练免疫可以改善免疫反应，并可作为在这一人群中对抗COVID-19的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.

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Deadly COVID-19 among the elderly: Innate immune memory helping those most in need.

Age is a key risk factor associated with the severity of symptoms caused by SARS-CoV-2, and there is an urgent need to reduce COVID-19 morbidity and mortality in elderly individuals. We discuss evidence suggesting that trained immunity elicited by BCG vaccination may improve immune responses and can serve as a strategy to combat COVID-19 in this population.

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Med (New York, N.y.)

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