COVID-19 时代的皇帝综合征:以患者为中心的肾脏病学时代到来了吗?

Dimitra Bacharaki, Athanasios Diamandopoulos
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摘要

冠状病毒病-19(COVID-19)大流行给我们敲响了警钟,迫使我们在全球范围内做出反应。就人力和财力成本而言,卫生政策和做法引起了特别关注。在 COVID-19 之前,慢性肾病已被认为是糖尿病和高血压患者的风险倍增因素,而现在这两种疾病已成为 COVID-19 感染和不良后果的主要风险因素。与迫切需要采取行动形成鲜明对比的是,肾脏病学领域对慢性肾脏病患者的管理却处于停滞状态,这些患者的发病率和死亡率仍然高得令人无法接受。具有讽刺意味且自相矛盾的是,在这个缺乏强有力临床试验的领域,临床实践是由基于薄弱证据的指南医学驱动的。皇帝综合症指的是安徒生的童话故事,在医学中被描述为对一个显而易见的事实自愿视而不见,即基于薄弱证据的治疗干预或薄弱的医疗保健。钠-葡萄糖共转运体 2 抑制剂是改善心脏和肾脏预后的一个很有希望的正面例子。COVID-19 可以促进以患者为中心的护理行动,成为肾脏病护理的积极转变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emperor's syndrome in the COVID-19 era: Time for patient-centered nephrology?

The coronavirus disease-19 (COVID-19) pandemic has been a wake-up call in which has forced us to react worldwide. Health policies and practices have attracted particular attention in terms of human and financial cost. Before COVID-19, chronic kidney disease was already considered a risk multiplier in patients with diabetes and hypertension, the two now being the major risk factors for COVID-19 infection and adverse outcome. In contrast to the urgent need for action, the nephrology field is considered to be in a state of stagnation regarding the management of chronic kidney disease patients who still experience unacceptably high morbidity and mortality. Ironically and paradoxically in a field lacking robust clinical trials, clinical practice is driven by guidelines-based medicine on weak evidence. The Emperor's syndrome, referring to Hans Christian Andersen's fairy tale, has been described in medicine as voluntary blindness to an obvious truth, being a weak evidence-based therapeutic intervention or weak health care. A promising positive example of improving heart and kidney outcomes is the emerging treatment with sodium-glucose cotransporter 2 inhibitors. COVID-19 could boost actions for patient-centered care as a positive shift in nephrology care.

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