Sebastian Kotz, Lisa Pechtold, Rudolf A Jörres, Dennis Nowak, Adam M Chaker
{"title":"职业鼻炎。","authors":"Sebastian Kotz, Lisa Pechtold, Rudolf A Jörres, Dennis Nowak, Adam M Chaker","doi":"10.5414/ALX02165E","DOIUrl":null,"url":null,"abstract":"<p><p>Occupational rhinitis (OR) has so far received little attention even though it shares common pathophysiological features and trigger factors and is closely associated with occupational asthma (OA). Work-related exposure to certain substances, such as animal dander, is considered to be the main factor for the development of OR. The new EAACI definition of OR stresses the causal relationship between workplace exposure and onset of rhinitis symptoms as opposed to previous definitions that mainly focused on a temporal relationship between workplace exposure and occurrence of nasal symptoms. Also, it has been suggested to use the term \"work-related rhinitis\" for classifying the different forms of rhinitis associated with the workplace. These forms can be subdivided into allergic or non-allergic OR, which is due to causes and conditions related to a particular work environment, as well as work-exacerbated rhinitis, which is defined as a pre-existing rhinitis exacerbated by exposure at the workplace. Even though taking a detailed patient history is especially important when it comes to diagnosing OR, the gold standard for confirming the diagnosis is nasal provocation testing. Best possible symptomatic relief and prevention of development of OA constitute the main therapeutic objectives in OR. Treatment options consist of total avoidance of trigger substances (main goal), reduction of exposure to certain substances, and pharmacotherapy. Furthermore, it is important to note that allergic OR is an occupational disease in Germany (Berufskrankheit No 4301) and needs to be reported to health authorities.</p>","PeriodicalId":7485,"journal":{"name":"Allergologie Select","volume":"5 ","pages":"51-56"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841416/pdf/","citationCount":"1","resultStr":"{\"title\":\"Occupational rhinitis.\",\"authors\":\"Sebastian Kotz, Lisa Pechtold, Rudolf A Jörres, Dennis Nowak, Adam M Chaker\",\"doi\":\"10.5414/ALX02165E\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Occupational rhinitis (OR) has so far received little attention even though it shares common pathophysiological features and trigger factors and is closely associated with occupational asthma (OA). Work-related exposure to certain substances, such as animal dander, is considered to be the main factor for the development of OR. The new EAACI definition of OR stresses the causal relationship between workplace exposure and onset of rhinitis symptoms as opposed to previous definitions that mainly focused on a temporal relationship between workplace exposure and occurrence of nasal symptoms. Also, it has been suggested to use the term \\\"work-related rhinitis\\\" for classifying the different forms of rhinitis associated with the workplace. These forms can be subdivided into allergic or non-allergic OR, which is due to causes and conditions related to a particular work environment, as well as work-exacerbated rhinitis, which is defined as a pre-existing rhinitis exacerbated by exposure at the workplace. Even though taking a detailed patient history is especially important when it comes to diagnosing OR, the gold standard for confirming the diagnosis is nasal provocation testing. Best possible symptomatic relief and prevention of development of OA constitute the main therapeutic objectives in OR. Treatment options consist of total avoidance of trigger substances (main goal), reduction of exposure to certain substances, and pharmacotherapy. Furthermore, it is important to note that allergic OR is an occupational disease in Germany (Berufskrankheit No 4301) and needs to be reported to health authorities.</p>\",\"PeriodicalId\":7485,\"journal\":{\"name\":\"Allergologie Select\",\"volume\":\"5 \",\"pages\":\"51-56\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7841416/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Allergologie Select\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5414/ALX02165E\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergologie Select","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5414/ALX02165E","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
摘要
职业性鼻炎(Occupational rhinitis, OR)与职业性哮喘(Occupational asthma, OA)密切相关,但具有共同的病理生理特征和诱发因素,迄今为止受到的关注较少。与工作有关的接触某些物质,如动物皮屑,被认为是发展OR的主要因素。EAACI对OR的新定义强调工作场所暴露与鼻炎症状发作之间的因果关系,而不是以往主要侧重于工作场所暴露与鼻症状发生之间的时间关系的定义。此外,有人建议使用术语“与工作有关的鼻炎”来分类与工作场所相关的不同形式的鼻炎。这些形式可细分为过敏性或非过敏性or,这是由于与特定工作环境相关的原因和条件造成的,以及工作加重性鼻炎,这被定义为由于工作场所暴露而加剧的已有鼻炎。尽管在诊断OR时,详细的患者病史尤为重要,但确认诊断的黄金标准是鼻腔刺激试验。尽可能减轻症状和预防骨性关节炎的发展是手术室的主要治疗目标。治疗方案包括完全避免触发物质(主要目标),减少接触某些物质和药物治疗。此外,值得注意的是,过敏性OR在德国是一种职业病(Berufskrankheit No . 4301),需要向卫生当局报告。
Occupational rhinitis (OR) has so far received little attention even though it shares common pathophysiological features and trigger factors and is closely associated with occupational asthma (OA). Work-related exposure to certain substances, such as animal dander, is considered to be the main factor for the development of OR. The new EAACI definition of OR stresses the causal relationship between workplace exposure and onset of rhinitis symptoms as opposed to previous definitions that mainly focused on a temporal relationship between workplace exposure and occurrence of nasal symptoms. Also, it has been suggested to use the term "work-related rhinitis" for classifying the different forms of rhinitis associated with the workplace. These forms can be subdivided into allergic or non-allergic OR, which is due to causes and conditions related to a particular work environment, as well as work-exacerbated rhinitis, which is defined as a pre-existing rhinitis exacerbated by exposure at the workplace. Even though taking a detailed patient history is especially important when it comes to diagnosing OR, the gold standard for confirming the diagnosis is nasal provocation testing. Best possible symptomatic relief and prevention of development of OA constitute the main therapeutic objectives in OR. Treatment options consist of total avoidance of trigger substances (main goal), reduction of exposure to certain substances, and pharmacotherapy. Furthermore, it is important to note that allergic OR is an occupational disease in Germany (Berufskrankheit No 4301) and needs to be reported to health authorities.