{"title":"中性粒细胞和嗜酸性粒细胞:它们在哮喘和慢性阻塞性肺病中的出现、存在和消失的临床意义。","authors":"A P Watt, B C Schock, M Ennis","doi":"10.2174/1568010054526313","DOIUrl":null,"url":null,"abstract":"<p><p>Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.</p>","PeriodicalId":86954,"journal":{"name":"Current drug targets. Inflammation and allergy","volume":"4 4","pages":"415-23"},"PeriodicalIF":0.0000,"publicationDate":"2005-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/1568010054526313","citationCount":"59","resultStr":"{\"title\":\"Neutrophils and eosinophils: clinical implications of their appearance, presence and disappearance in asthma and COPD.\",\"authors\":\"A P Watt, B C Schock, M Ennis\",\"doi\":\"10.2174/1568010054526313\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.</p>\",\"PeriodicalId\":86954,\"journal\":{\"name\":\"Current drug targets. Inflammation and allergy\",\"volume\":\"4 4\",\"pages\":\"415-23\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2174/1568010054526313\",\"citationCount\":\"59\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current drug targets. Inflammation and allergy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1568010054526313\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current drug targets. Inflammation and allergy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1568010054526313","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Neutrophils and eosinophils: clinical implications of their appearance, presence and disappearance in asthma and COPD.
Asthma and chronic obstructive pulmonary disease (COPD) are common chronic disorders. Traditionally, asthma has been associated with an eosinophilic inflammation and COPD with neutrophilic inflammation. In this review we will highlight the maturation, recruitment, activation, action and apoptosis of these cells. In addition we will focus on the evidence for their presence in disease and suggest potential new therapeutic interventions.
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