{"title":"应用SNP基因分型和遥感技术研究多基因和环境因素对皮肤色素沉着表型个体间变异的影响。","authors":"Sumiko Anno, Susumu Kudo, Keita Hamasaki, Kazunari Matsumura, Takushi Yamamoto, Koretsugu Ogata","doi":"10.2114/jpa.24.483","DOIUrl":null,"url":null,"abstract":"<p><p>We present a conceptual framework for applying techniques of SNP genotyping as a molecular biological approach and remote sensing as an ecological approach to elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype. Additionally, we discuss the obstacles that frustrate our efforts to identify how the human genome encodes the complex phenotype and suggest the use of computational methods designed for knowledge discovery within hereditary database.</p>","PeriodicalId":80293,"journal":{"name":"Journal of physiological anthropology and applied human science","volume":"24 4","pages":"483-6"},"PeriodicalIF":0.0000,"publicationDate":"2005-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2114/jpa.24.483","citationCount":"2","resultStr":"{\"title\":\"Techniques of SNP genotyping and remote sensing applied for elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype.\",\"authors\":\"Sumiko Anno, Susumu Kudo, Keita Hamasaki, Kazunari Matsumura, Takushi Yamamoto, Koretsugu Ogata\",\"doi\":\"10.2114/jpa.24.483\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We present a conceptual framework for applying techniques of SNP genotyping as a molecular biological approach and remote sensing as an ecological approach to elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype. Additionally, we discuss the obstacles that frustrate our efforts to identify how the human genome encodes the complex phenotype and suggest the use of computational methods designed for knowledge discovery within hereditary database.</p>\",\"PeriodicalId\":80293,\"journal\":{\"name\":\"Journal of physiological anthropology and applied human science\",\"volume\":\"24 4\",\"pages\":\"483-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.2114/jpa.24.483\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of physiological anthropology and applied human science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2114/jpa.24.483\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of physiological anthropology and applied human science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2114/jpa.24.483","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Techniques of SNP genotyping and remote sensing applied for elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype.
We present a conceptual framework for applying techniques of SNP genotyping as a molecular biological approach and remote sensing as an ecological approach to elucidation of the contribution of polygene and environmental factors to inter-individual variation in skin pigmentation phenotype. Additionally, we discuss the obstacles that frustrate our efforts to identify how the human genome encodes the complex phenotype and suggest the use of computational methods designed for knowledge discovery within hereditary database.