Dr. Hervé Fernandez M.D. , Dr. Antoine Watrelot M.D. , Dr. Jean-Dominique Alby M.D. , Dr. Jacques Kadoch M.D. , Dr. Amélie Gervaise M.D. , Dr. Renaud deTayrac M.D. , Dr. René Frydman M.D.
{"title":"经阴道卵巢镜穿刺治疗多囊卵巢综合征后的生育能力","authors":"Dr. Hervé Fernandez M.D. , Dr. Antoine Watrelot M.D. , Dr. Jean-Dominique Alby M.D. , Dr. Jacques Kadoch M.D. , Dr. Amélie Gervaise M.D. , Dr. Renaud deTayrac M.D. , Dr. René Frydman M.D.","doi":"10.1016/S1074-3804(05)60054-0","DOIUrl":null,"url":null,"abstract":"<div><h3>Study Objective</h3><p>To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).</p></div><div><h3>Design</h3><p>Prospective study (Canadian Task Force classification II).</p></div><div><h3>Setting</h3><p>University teaching hospital and private clinic.</p></div><div><h3>Patients</h3><p>Eighty women with clomiphene citrate-resistant PCOS.</p></div><div><h3>Intervention</h3><p>Operative transvaginal fertiloscopy with a coaxial bipolar electrode.</p></div><div><h3>Measurements and Main Results</h3><p>During a mean follow-up of 18.1 months (± 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1–11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.</p></div><div><h3>Conclusion</h3><p>Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.</p></div>","PeriodicalId":79466,"journal":{"name":"The Journal of the American Association of Gynecologic Laparoscopists","volume":"11 3","pages":"Pages 374-378"},"PeriodicalIF":0.0000,"publicationDate":"2004-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1074-3804(05)60054-0","citationCount":"51","resultStr":"{\"title\":\"Fertility after Ovarian Drilling by Transvaginal Fertiloscopy for Treatment of Polycystic Ovary Syndrome\",\"authors\":\"Dr. Hervé Fernandez M.D. , Dr. Antoine Watrelot M.D. , Dr. Jean-Dominique Alby M.D. , Dr. Jacques Kadoch M.D. , Dr. Amélie Gervaise M.D. , Dr. Renaud deTayrac M.D. , Dr. René Frydman M.D.\",\"doi\":\"10.1016/S1074-3804(05)60054-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Study Objective</h3><p>To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).</p></div><div><h3>Design</h3><p>Prospective study (Canadian Task Force classification II).</p></div><div><h3>Setting</h3><p>University teaching hospital and private clinic.</p></div><div><h3>Patients</h3><p>Eighty women with clomiphene citrate-resistant PCOS.</p></div><div><h3>Intervention</h3><p>Operative transvaginal fertiloscopy with a coaxial bipolar electrode.</p></div><div><h3>Measurements and Main Results</h3><p>During a mean follow-up of 18.1 months (± 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1–11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.</p></div><div><h3>Conclusion</h3><p>Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.</p></div>\",\"PeriodicalId\":79466,\"journal\":{\"name\":\"The Journal of the American Association of Gynecologic Laparoscopists\",\"volume\":\"11 3\",\"pages\":\"Pages 374-378\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2004-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S1074-3804(05)60054-0\",\"citationCount\":\"51\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of the American Association of Gynecologic Laparoscopists\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1074380405600540\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of the American Association of Gynecologic Laparoscopists","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1074380405600540","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fertility after Ovarian Drilling by Transvaginal Fertiloscopy for Treatment of Polycystic Ovary Syndrome
Study Objective
To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).
Design
Prospective study (Canadian Task Force classification II).
Setting
University teaching hospital and private clinic.
Patients
Eighty women with clomiphene citrate-resistant PCOS.
Intervention
Operative transvaginal fertiloscopy with a coaxial bipolar electrode.
Measurements and Main Results
During a mean follow-up of 18.1 months (± 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1–11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.
Conclusion
Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.