经阴道卵巢镜穿刺治疗多囊卵巢综合征后的生育能力

Dr. Hervé Fernandez M.D. , Dr. Antoine Watrelot M.D. , Dr. Jean-Dominique Alby M.D. , Dr. Jacques Kadoch M.D. , Dr. Amélie Gervaise M.D. , Dr. Renaud deTayrac M.D. , Dr. René Frydman M.D.
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引用次数: 51

摘要

研究目的评价双极能量法在抗枸橼酸克罗米芬多囊卵巢综合征(PCOS)中的应用价值。前瞻性研究(加拿大特别工作组分类II)。环境:大学教学医院和私人诊所。患者:克罗米芬耐药多囊卵巢综合征患者80例。同轴双极电极经阴道生殖镜介入术。在平均18.1个月(±6.4)个月的随访中,73例(91%)妇女恢复了正常的排卵周期。自发周期和刺激周期的累计妊娠率为60%(44/73),其中39.7%(29/73)归因于单独钻井。平均怀孕时间为3.9个月(范围1-11.8)。有8例流产(18%),无异位妊娠或多胎妊娠。无并发症发生。结论经阴道生殖镜下双极电刀卵巢钻孔治疗对枸橼酸克罗米芬耐药的PCOS是一种有效的微创治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fertility after Ovarian Drilling by Transvaginal Fertiloscopy for Treatment of Polycystic Ovary Syndrome

Study Objective

To evaluate fertiloscopy ovarian drilling with bipolar energy in women with clomiphene citrate-resistant polycystic ovary syndrome (PCOS).

Design

Prospective study (Canadian Task Force classification II).

Setting

University teaching hospital and private clinic.

Patients

Eighty women with clomiphene citrate-resistant PCOS.

Intervention

Operative transvaginal fertiloscopy with a coaxial bipolar electrode.

Measurements and Main Results

During a mean follow-up of 18.1 months (± 6.4), 73 women (91%) recovered regular and ovulatory cycles. The cumulative pregnancy rate was 60% (44/73) for spontaneous and stimulated cycles, with 39.7% (29/73) imputed to drilling alone. The mean time to conceive was 3.9 months (range 1–11.8). There were eight miscarriages (18%), and no ectopic pregnancies or multiple pregnancy. No complications occurred.

Conclusion

Ovarian drilling by transvaginal fertiloscopy with bipolar electrosurgery appears to be an effective minimally invasive procedure in patients with PCOS resistant to clomiphene citrate.

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