血液透析患者的脂蛋白(a)。

Acta medica Austriaca Pub Date : 2004-08-01
José Antonio Díaz-Peromingo, Dolores Güimil Carbajal, Ana Albán-Salgado
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引用次数: 0

摘要

脂蛋白(a) [Lp(a)]可能通过调节纤溶系统产生血栓形成作用。Lp(a)水平升高也与动脉粥样硬化风险增加有关。由于动脉粥样硬化在终末期肾病患者中更为普遍,我们分析了Lp(a)在血液透析患者中的作用。对20例患者进行了研究。Lp(a)分别在血液透析前后及后续透析前测定。在第一和第二测量之间没有统计学差异,但当比较第一和第三测量时,发现了统计学差异(增加)。总之,发现了Lp(a)水平的变化,这些变化可能与影响血液透析患者的间歇性炎症有关。这些变化的意义以及在加速终末期肾病患者动脉粥样硬化中的作用尚不清楚。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lipoprotein (a) in patients on hemodialysis.

Lipoprotein (a) [Lp(a)] may produce thrombogenic effects by modulating the fibrinolytic system. Elevated levels of Lp(a) have also been associated with an increased risk for atherosclerosis. Because atherosclerosis is more prevalent among patients with end-stage renal disease, the role of Lp(a) among patients on hemodialysis is analyzed. Twenty patients were studied. Lp(a) was measured before and after a hemodialysis session and before the following session. Between the first and second measures there was no statistical difference but when first and third measures were compared, a statistical difference (increase) was found. In conclusion, changes in Lp(a) levels were found and perhaps these changes are related to the episodic inflammation affecting patients on hemodialysis. The significance of these changes and the role in accelerating atherosclerosis in patients with end-stage renal disease are unknown.

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