儿科麻醉:吸入还是静脉注射?

Anaesthesiologie und Reanimation Pub Date : 2004-01-01
M Jöhr
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引用次数: 0

摘要

全静脉麻醉最近在儿科麻醉中获得了更多的兴趣。然而,儿童的全球经验是有限的,因此,在成人实践中获得的知识往往不加批判地应用于儿科患者。口罩诱导麻醉是一种广泛使用和普遍接受的技术;自从七氟烷进入临床实践以来,它得到了更大的普及。由于减少了心血管的副作用,该药明显提高了安全性。静脉通路的可用性是静脉诱导的先决条件。注射时疼痛、心动过缓和给药困难是主要的缺点。吸入麻醉剂可以监测每一次呼吸的个体药代动力学。另一方面,通过静脉输注异丙酚来维持麻醉主要是基于假设,即使是通过计算机控制的泵给药。个体患者可能出现与预测值的较大偏差。术中意识是可能的,但其发生率通常被低估。静脉输注和泵功能障碍是静脉注射技术的典型并发症。减少术后呕吐和躁动的发生率是公认的静脉注射技术的优点。异丙酚输注综合征是儿童和成人长期输注引起的。它甚至可以在使用该物质几个小时后发生。给药安全期的持续时间是完全未知的,特别是对新生儿和婴儿。总之,这两种方法都可以用于儿童;两者都有优点和缺点。因为对小孩子的经验非常有限,我们必须每天用批判的眼光重新评估我们的做法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Paediatric anaesthesia: inhaled or intravenous technique?].

Total intravenous anaesthesia has recently gained more interest in paediatric anaesthesia. However, the global experience with children is limited, therefore, the knowledge acquired in adult practice is often applied uncritically to the paediatric patient. Induction of anaesthesia by mask is a widely used and generally accepted technique; it has gained even more popularity since the introduction of sevoflurane into clinical practice. This drug has markedly improved the safety because of the reduced cardiovascular side-effects. The availability of venous access is a prerequisite for intravenous induction. Pain on injection, bradycardia, and difficulties in dosing the individual patient are the main drawbacks. Inhaled anaesthetics allow to monitor breath by breath the individual pharmacokinetics. On the other hand, maintenance of anaesthesia by an intravenous infusion of propofol is mainly based on assumptions, even when the drug is administered by computer-controlled pumps. Large aberrations from the predicted values can occur in the individual patient. Intraoperative awareness is possible, however, its incidence is generally underestimated. Paravenous infusion and pump dysfunction are typical complications of an intravenous technique. A reduced incidence of postoperative vomiting and agitation are recognised advantages of an intravenous technique. Propofol-infusion-syndrome results from prolonged administration in children and in adults. It can even occur after the use of the substance for a few hours. The duration of a safe period for administration is completely unknown, especially for neonates and infants. In summary, both techniques can be used in children; both have advantages and drawbacks. Because the experience with small children is very limited, we have to re-evaluate our practice with a critical eye day by day.

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