食管癌手术的早期结果。

R Konopke, S Kersting, D Ockert, J Gastmeier, H D Saeger
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引用次数: 3

摘要

目的:本研究的目的是评估食管癌切除术的早期结果,包括评估术前危险因素和术后死亡率(Barthels et al. 1998制定的风险评分)。方法:1993年10月至2002年12月对181例食管癌患者进行手术治疗。在前瞻性分析中,回顾了患者的特点,食管癌的特点,食管癌切除的部位和类型,根治性,并发症和死亡率。结论:143例(79.0%)成功切除肿瘤。总并发症发生率为52.5%,以心肺并发症为主(25.9%)。术后并发症以吻合口漏(12.6%)和复发性神经损伤(9.1%)为主。颈吻合术食管切除术后两种并发症发生率均显著高于颈吻合术(p = 0.03和p < 0.01)。住院死亡率为8.4%。30天死亡率为4.9%。使用术前风险评分进行回顾性和前瞻性分析,我们的数据显示低风险患者(2.4%和2.3%)的死亡率低于中风险患者(7.4%和6.4%)。唯一的高风险患者在切除后死亡。讨论与总结:本分析结果表明,食管癌切除术可以在可接受的发病率和死亡率下完成。但是,必须考虑到术前因素的增加会导致术后死亡率的增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Early results of esophageal surgery in carcinoma].

Aims: The aim of this study was the evaluation of early results of esophageal resection for cancer including the assessment of pre-operative risk factors and post-operative mortality (risk score developed by Barthels et al. 1998).

Methods: One hundred and eighty one patients with esophageal cancer were operated with curative intention between October 1993 and December 2002. In a prospective analysis were reviewed: patient characteristics, characteristics of the esophageal cancer, part and type of esophageal resection, radicality, complications and mortality.

Conclusion: In total, a resection of the tumor could be achieved in 143 cases (79.0%). The overall complication rate was 52.5%, mainly cardio-pulmonary complications (25.9%) were seen. The surgical complications were determined by anastomotic leak (12.6%) and recurrent nerve injury (9.1%). Both types of complications were observed significantly more often after esophageal resection with a cervical anastomosis (p = 0.03 and p < 0.01). The hospital mortality was 8.4%. The 30 days mortality was 4.9%. Using a preoperative risk score retro- and prospectively, our data showed a lower mortality in patients with a low risk profile (2.4% and 2.3%) compared to those with a medium risk profile (7.4% and 6.4%). The only patient with a high risk profile died after resection.

Discussion and summary: The results of this analysis show that resection of esophageal cancer can be accomplished with acceptable morbidity and mortality. However, it has to be taken into account that the increase of pre-operative factors leads to an increase in post-operative mortality.

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