[口腔鳞状细胞癌中I型胶原的表达]。

Q2 Dentistry

Pesquisa odontologica brasileira = Brazilian oral research Pub Date : 2003-01-01 Epub Date: 2003-08-05 DOI:10.1590/s1517-74912003000100016

Gabriela Botelho Martins, Sílvia Regina Reis, Tânia Maria Silva

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引用次数: 11

摘要

对口腔鳞状细胞癌侵袭前的细胞外基质的分析可以提高对恶性肿瘤生长过程中肿瘤细胞基质相互作用的理解。胶原I表达的改变可能影响细胞的侵袭和转移。本文将23例鳞状细胞癌纳入Anneroth恶性分级系统。采用h.e.和天狼星红染色。I型胶原蛋白的免疫组化表达在不同恶性肿瘤评分中观察。因此，我们观察到口腔鳞状细胞癌的细胞外基质在低评分和高评分的恶性肿瘤中表现出不同的胶原I表达模式。

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查看原文本刊更多论文

[Collagen type I expression in squamous cell carcinoma of the oral cavity].

An analysis of the extracellular matrix at the invasive front of squamous cell carcinoma of the oral cavity may improve the understanding of tumour cell matrix interactions during malignancy growth. Alterations in collagen I expression may influence cellular invasion and metastasis. In this work, 23 cases of squamous cell carcinoma were submitted to the Anneroth's malignancy grading system. H. E. and sirius red staining were used. Immuno-histochemical expression of collagen type I protein was observed in different malignancy scores. As a result, it was observed that the extracellular matrix in squamous cell carcinoma of the oral cavity shows different patterns of collagen I expression in low and high scores of malignancy.

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来源期刊

Pesquisa odontologica brasileira = Brazilian oral research Dentistry-Dentistry (all)

CiteScore

3.80

自引率

0.00%

发文量

期刊介绍： Pesquisa Odontológica Brasileira is a new quarterly published journal (January-March, April-June, July-September, October-December), with an annual supplement (Anais da Reunião de Pesquisa Odontológica da SBPqO), by the Sociedade Brasileira de Pesquisa Odontológica [Brazilian Society of Odontological Research] and University of São Paulo. It replaces Revista de Odontologia da Universidade de São Paulo (ISSN 0103-0663).