二茂铁乙酰萘二亚胺作为一种新的DNA传感电化学配体。

S Sato, K Yamashita, M Takagi, S Takenaka
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引用次数: 4

摘要

用二茂铁乙酸在萘二亚胺的两个亚胺取代基末端氨基上连接,合成了新的电化学活性DNA配体1。在含有DMSO的水溶液中进行的电化学实验表明,配体1对双链DNA的选择性比先前报道的配体2有所提高。1的峰值电流从2的峰值电流向负方向移动,从而缩短了基因检测所需的时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ferroceneacetyl naphthalene diimide as a new electrochemical ligand for DNA sensing.

New electrochemically active DNA ligand 1 was synthesized by the connection of ferroceneacetic acid at the terminal amino moieties of two imide substituents of naphthalene diimide. Electrochemical experiments in aqueous solution containing DMSO showed that the selectivity for double stranded DNA of 1 has increased from that of ligand 2 previously reported. The peak current of 1 shifted toward the negative side from that of 2, thereby shortening the time required for gene detection.

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