[肥胖——一个危险因素]。

Sbornik lekarsky Pub Date : 2002-01-01
P Hlúbik, L Opltová, J Chaloupka
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引用次数: 0

摘要

1997年和1998年,对捷克共和国12个地区的859名消防救援服务男性成员的营养状况进行了评估。该研究提供了有关选定的人体测量和生化参数的广泛信息,特别是那些通常用作心血管疾病(CVD)起源和发展的风险指标:体重指数(BMI)、体脂百分比(b. fat)、腰围(腰围)、血清总胆固醇(Tchol)浓度、HDL-和ldl -胆固醇(HDL-chol, LDL-chol)、甘油三酯(TAG)和动脉粥样硬化指数(AI)。在血脂参数方面,30.4% (TAG)、54% (Tchol)和60.9% (LDL-chol)的志愿者血清水平升高。38.2%的志愿者血清高密度脂蛋白胆固醇水平下降。79.9%的受试者计算出AI高于3.5 a.u., 45.3%的受试者计算出AI高于5.0 a.u.。62%的正常体重男性、85%的超重男性和92%的肥胖男性的AI高于3.5 a.u.。研究结果证明,超重和肥胖在随后的男性人群中相当普遍:根据计算的BMI,估计有49.5%的志愿者超重,16.3%的志愿者肥胖。该研究概念使揭示人体测量和生化参数之间的关系成为可能。相关矩阵显示BMI或腰围值与Tchol、LDL-chol、TAG和AI的血清浓度有统计学意义的相关性。高密度脂蛋白胆固醇血清浓度与BMI或腰围值呈显著负相关。方差分析结果(估计的脂质参数值根据BMI和腰围类别分组)显示,35岁以上年龄组的血清Tchol、LDL-chol、TAG和AI与25岁以下年龄组相比有统计学意义的升高。对于高胆固醇和低密度脂蛋白胆固醇,在25-35岁年龄组中已经发现了统计学上显著的增加。与正常体重组相比,超重和肥胖组的Tchol血清水平和AI值均有统计学意义上的升高。结果表明,超重组和超重组血清TAG和ldl -胆固醇水平均显著升高。和肥胖类别。与正常体重组相比,超重组和肥胖组的高密度脂蛋白胆固醇血清水平均有统计学上的显著下降。同样,与低风险CVD组相比,高、高风险CVD组(根据腰围值)的Tchol、LDL-chol、TAG血清浓度和AI值均增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Obesity--a risk factor].

The nutritional status of a selected population--859 male members of the Fire Rescue Service from 12 districts in the Czech Republic--was assessed in 1997 and 1998. The study provides extensive information on selected anthropometrical and biochemical parameters, especially on those, which are generally used as risk indices for the origin and development of cardiovascular disease (CVD): body mass index (BMI), body fat percentage (b. fat), waist circumference (waist), serum concentrations of total cholesterol (Tchol), HDL- and LDL-cholesterol (HDL-chol, LDL-chol), triacylglyceroles (TAG) and the atherogenic index (AI). As far as lipid parameters were concerned, increased serum levels were estimated in 30.4% (TAG), 54% (Tchol) and 60.9% (LDL-chol) of volunteers. Decreased serum levels of HDL-chol were found in 38.2% of volunteers. An AI higher than 3.5 a.u. was calculated for 79.9% of all subjects in study while an AI higher than 5.0 a.u. was calculated for 45.3% of all subjects. An AI higher than 3.5 a.u. was found in 62% of males with normal weight, in 85% of overweight males and in 92% of obese males. The results of the study proved the considerable prevalence of the overweightness and obesity in the male population group that was followed: according to the calculated BMI, 49.5% of volunteers were estimated to be overweight and 16.3% to be obese. The study concept made it possible to reveal the relationships among the anthropometrical and biochemical parameters followed. The correlation matrix documents a statistically significant dependence among the BMI or waist values and the serum concentrations of Tchol, LDL-chol, TAG and AI. A significant negative correlation was found between the HDL-chol serum concentration and the BMI or waist values. The variance analysis results (the estimated lipid parameter values were divided into groups according to BMI and waist categories) document a statistically significant increase in serum Tchol, LDL-chol, TAG and AI in age categories over 35 years in comparison with the category of men under 25 years of age. For Tchol and LDL-chol a statistically significant increase had already been found in the 25-35 year age category. In comparison with the normal weight category, Tchol serum levels and AI values were statistically significantly higher in both the overweight and obese categories. Statistically significant increase was proven for the TAG and LDL-chol serum levels in both the overweight II. gr. and obese categories. A statistically significant decrease in comparison with the normal weight category was found in the HDL-chol serum levels of both the overweight and obesity categories. In the same way, an increase in Tchol and LDL-chol, TAG serum concentrations and AI values in higher and high risk CVD categories (according to the waist circumference value) was found in comparison with the low CVD risk category.

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