2型糖尿病药物治疗的现代途径

Voprosy meditsinskoi khimii Pub Date : 2002-07-01
I R Kovel'man, A I Tochilkin, N F Beliaeva, V K Gorodetskiĭ, V A Kniazhev, S B Tkachenko, L L Semenov, N V Semenova
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引用次数: 0

摘要

综述了2型糖尿病的药理治疗方法。特别注意的是新的治疗药物,能够降低血糖水平。讨论了其降糖作用的可能机制。简而言之,瑞帕苷、那格列奈和α -葡萄糖苷酶抑制剂可预防餐后低血糖,噻唑烷二酮类可改善对胰岛素的敏感性,钒化合物可作为胰岛素作用增强剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Modern approaches to pharmacotherapy of diabetes mellitus type II].

The pharmacological approaches to the treatment of type 2 diabetes mellitus were reviewed. Special attention was paid to the new therapeutic agents that are able to decrease plasma glucose levels. The possible mechanisms of the hypoglycemic effects are discussed. Briefly, repaginide, nateglinede and alpha-glucosidase inhibitors prevent postprandial hypoclycemia while thiazaolidinediones improve the sensitivity to insulin and vanadium compounds act as an insulin action enhancer.

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