泰国志愿者测试艾滋病毒疫苗。

Vaccine weekly Pub Date : 1994-12-12
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引用次数: 0

摘要

30名泰国志愿者接受了最后一次注射,医生们认为这是一种很有前途的实验性艾滋病疫苗。泰国项目负责人帕潘·帕努帕克(Prapan Panupark)博士说,他对25名男性和5名女性进行的初步测试结果感到鼓舞。这种实验性疫苗被称为联合生物医学公司合成单价HIV-1肽,研究对象是年龄在21岁至48岁之间的健康志愿者。普拉潘在新闻发布会上说,参与者在1994年6月6日接受了第一次注射,在1994年7月4日接受了第二次注射,在1994年11月28日接受了最后一次注射。他说,巴西和乌干达也在进行类似的检测,这两个国家和泰国一样,都是艾滋病的重灾区。Prapan说,在第二次注射一个月后,血液测试显示,在24名接种疫苗的志愿者中,有10人产生了免疫力。他说:“我们很高兴在24个病例中有10个产生了免疫力,即超过40%。”“我们很高兴,因为在美国和澳大利亚等其他国家进行的类似测试中,只有约20%的志愿者产生了免疫力。”他说,志愿者将再接受三次血液检测,以确定他们的免疫水平。根据最近公布的数据,在过去的十年里,泰国有3902人死于艾滋病。泰国还有5215名艾滋病晚期患者,据估计有60万人被认为是艾滋病毒阳性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thai volunteers test HIV vaccine.

A group of 30 Thai volunteers received their final injections in a multi-national test of what doctors believe is a promising experimental AIDS vaccine. Dr. Prapan Panupark, director of the project in Thailand, said he was encouraged by initial results of the test conducted on 25 males and five females. The study of the experimental vaccine, known as the United Biomedical Inc. synthetic monovalent HIV-1 peptide, involved healthy volunteers aged from 21 to 48. Prapan told a press conference that participants received their first injections on June 6, 1994, another on July 4, 1994, and their final shot November 28, 1994. He said similar tests are taking place in Brazil and Uganda, which, like Thailand, have been hard-hit by HIV. One month after the second injection, Prapan said, blood tests revealed that out of 24 volunteers receiving the vaccine, 10 had developed immunity. "We are happy that immunity developed in 10 cases out of 24, or over 40%," he said. "We are happy because in similar tests in other countries, such as the US and Australia, only about 20% of the volunteers developed immunity." He said the volunteers will have their blood tested three more times to determine their levels of immunity. According to recently released figures, 3902 people have died of AIDS in Thailand in the past decade. Another 5215 patients are suffering from advanced AIDS in Thailand, while an estimated 600,000 people are believed to be HIV-positive.

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