描述费尔斯儿童连续身高数据的多相方法:一个六语-逻辑-加性生长模型。

Growth Development and Aging Pub Date : 2000-02-01
J T Walker, O A Walker
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引用次数: 0

摘要

本文报道了80例费尔斯儿童身高序列数据的拟合结果。该模型假设人体身高增长曲线是六个宏观logistic增长过程的综合作用,每个过程都达到相同的渐近身高值。它被命名为Walker和Walker- hexaphasic - logistics - additive (WWHLA)增长模型。使用该模型的一个优点是,它使我们能够轻松地拟合整个生长曲线与14个生物学上可解释的参数。我们使用计算机化的非线性最小二乘技术对模型进行了测试。结果表明,新模型工作得非常好。拟合的结果是R、R2和调整后的R2值较高,F值较大,残差均方相对较低,Durbin-Watson统计量非常接近2,模型参数的标准误差估计相对较小。此外,95%以上的儿童通过了正态性和常方差检验,残差图基本上没有模型偏差。新模型确定了男性和女性生长曲线中的六个生长成分或过程。这些过程是根据它们达到最高高度速度的时间来命名的:新生儿期、婴儿期、幼儿期、中期、晚期和青春期。初步结果表明,WWHLA模型似乎是目前可用来描述人类生长曲线的最佳模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A multiphasic approach for describing serial height data of Fels children: a hexaphasic-logistic-additive growth model.

In this paper, we reported the results obtained from fitting a new growth model to serial height data of 80 Fels children. The model assumed that human height growth curves are due to the combined effects of six macroscopic logistic growth processes, each reaching the same asymptotic height value. It was named the Walker and Walker-Hexaphasic-Logistic-Additive (WWHLA) growth model. An advantage to using this model is that it allowed us to easily fit entire growth curves with 14 biologically interpretable parameters. We tested the model using a computerized nonlinear least squares technique. The results showed that the new model worked extremely well. The fits resulted in high R, R2, and adjusted R2 values, large F values, relatively low residual mean squares, Durbin-Watson statistics that were very close to 2, and relatively small standard error estimates for the model parameters. In addition, the normality and constant variance test passed for more than 95 percent of the children, and the graphs of the residuals essentially showed no model bias. The new model identified the six growth components or processes in both male and female growth curves. The processes were named according to when they reached their peak height velocity: neonatal, infantile, early-childhood, middle-childhood, late-childhood, and pubertal. Preliminary results suggest that the WWHLA model appears to be the best that is currently available at this time for describing the human growth curve.

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