胰腺导管内乳头状粘液瘤(非侵袭性腺癌)发病27年后切除1例。

Y Shimizu, K Yasui, T Morimoto, A Torii, K Yamao, K Ohhashi
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引用次数: 23

摘要

本文报告一例胰腺导管内乳头状粘液瘤(IPMT)在发病27年后切除。1997年3月,一位71岁的老人因严重的上腹部疼痛住进我院。患者于1971年4月首次在我院行内镜逆行胰脏造影(ERP),随访26年胰脏造影改变。随访期间主胰管扩张逐渐进展,肿瘤所致充盈缺损明显。入院时,ERP显示主胰管弥漫性扩张,直径20 mm,充盈缺损直径35 mm。我们诊断这个病人患有胰脏IPMT。考虑患者的一般情况,行胰段切除术,术后病程良好。组织学表现与非侵袭性乳头状腺癌一致。这是研究胰腺导管内乳头状瘤的自然史和评估手术应用的宝贵病例,因为该肿瘤的生物学行为远低于胰腺导管细胞癌的侵袭性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case of intraductal papillary mucinous tumor (noninvasive adenocarcinoma) of the pancreas resected 27 years after onset.

A case of intraductal papillary mucinous tumor (IPMT) of the pancreas resected 27 yr after onset is presented. In March of 1997, a 71-yr-old man was admitted to our hospital with a complaint of severe epigastric pain. He had initially undergone endoscopic retrograde pancreatography (ERP) in April 1971 in our hospital and the patient had been followed up for pancreatografic changes for 26 yr. Dilatation of the main pancreatic duct gradually progressed during follow-up, and the filling defect owing to the tumor became demonstrable. On admission, ERP revealed diffuse dilatation of the main pancreatic duct, which was 20 mm in diameter, and the filling defect of 35 mm in diameter. We diagnosed this patient as having an IPMT of the pancreas. Considering his general condition, pancreatic segmentectomy was carried out, and the postoperative course was favorable. Histological findings were compatible with those of noninvasive papillary adenocarcinoma. This is a precious case for studying the natural history of intraductal papillary tumor of the pancreas and to evaluate the application of surgery, because the biologic behavior of this tumor is much less aggressive than that of pancreatic ductal cell carcinoma.

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