从临床样本中筛选抗阿昔洛韦的单纯疱疹病毒分离株。

I W Mah, B I Kuo, H Y Wei, C H Tsai, W T Liu
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引用次数: 0

摘要

采用菌斑减少法测定无环鸟苷对VGH-Taipei地区分离的单纯疱疹病毒株的ID90和ID50值。对20个80年代(1980-1985年)和30个90年代(1990-1995年)的HSV分离株进行菌斑减少试验,对阿昔洛韦进行药敏试验。90年代有15株HSV分离株的ID90高于80年代,表明90年代出现了更多耐阿昔洛韦分离株的趋势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Screening for acyclovir-resistant herpes simplex virus isolates from clinical samples.

The ID90 or ID50 values of acyclovir for the herpes simplex virus strains isolated in VGH-Taipei were determined by plaque reduction method. Twenty HSV isolates of 1980's (1980-1985) and thirty of 1990's (1990-1995) were subjected to plaque reduction assay for susceptibility test to acyclovir. There were fifteen HSV isolates of 1990's whose ID90 were higher than those of 1980's, indicating a trend of more acyclovir resistant isolates in 1990's.

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