副溶血性弧菌菌血症1例。

Changgeng yi xue za zhi Pub Date : 1999-09-01
T C Ng, P C Chiang, T L Wu, H S Leu
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摘要

副溶血性弧菌(V. paraholyticus)是一种生活在海洋中的嗜盐革兰氏阴性杆菌。在台湾,它是导致感染性腹泻的主要原因,有时会引起软组织感染,但很少引起菌血症。文献中仅报道了11例。大多数病例都有食用海产品或接触海水的历史。此外,这些患者均有免疫抑制,特别是白血病和肝硬化患者。我们报告一位60岁男性慢性丙型肝炎合并肾上腺功能不全的病患。他在入院前一周食用海鲜后出现副溶血性弧菌菌血症。他的病情复杂,颈部和右下肢软组织感染,以及多器官衰竭。患者经静脉注射头孢他啶、口服强力霉素和手术清创后存活。据我们所知,这是Medline上报告的第12例病例,也是台湾的第二例菌血症病例。在回顾文献后,我们建议所有免疫抑制或肾上腺功能不全的患者应食用煮熟的食物,避免生海鲜。此外,当患者在食用海鲜后出现发热、腹泻和软组织感染的危险时,应怀疑副溶血性弧菌感染。所有培养标本应接种于弧菌选择性培养基上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vibrio parahemolyticus bacteremia: case report.

Vibrio parahemolyticus (V. parahemolyticus) is a halophilic gram-negative bacillus that lives in the ocean. It is the leading cause of infectious diarrhea in Taiwan and sometimes produces soft tissue infections, but it is rarely a cause of bacteremia. There have been only 11 cases reported in the literature. Most of the cases involved a history of ingestion of seafood or exposure to seawater. In addition, those patients were all immunosuppressed, especially with leukemia and cirrhosis. We report a 60-year-old male patient with chronic hepatitis C and adrenal insufficiency. He developed V. parahemolyticus bacteremia following ingestion of seafood one week prior to admission. His condition was complicated with neck and right lower leg soft tissue infection, as well as multiple organ failure. The patient survived after intravenous ceftazidime, oral doxycycline, and surgical debridement. To our knowledge, this is the 12th reported cases on Medline, and the second bacteremic case in Taiwan. After reviewing the literature, we suggest that all patients with immunosuppressed conditions or adrenal insufficiency should eat foods that are well cooked and avoid raw seafood. Moreover, when patients who are at risk to develop fever, diarrhea, and soft tissue infection after ingestion of seafood, V. parahemolyticus infection should be suspected. All culture specimens should be inoculated on Vibrios selective media.

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