M von Janta-Lipinski, K Gaertner, C Lehmann, H Scheer, J Schildt, E Matthes
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Protein and RNA of human telomerase as targets for modified oligonucleotides.
Chimeric oligodeoxynucleotides containing phosphorothioate and N3'-->P5' phosphoramidate linkages were synthesized. These oligomers show a high inhibitory activity against human telomerase.