【胎兔手术技术】

G Feng, G Sun, X Yang
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引用次数: 0

摘要

目的:实验性胎儿手术已成为研究胎儿生长发育和创面愈合的常用方法。兔子仍然是一种合理的动物模型。实验成功的关键在于将手术动物的存活率保持在80%以上。本文介绍了一种简单的家兔胎儿手术实验方法。方法:采用硫喷妥钠静脉全麻。手术是在子宫内通过子宫切开或将胎儿的尾侧部分取出子宫进行的。羊水通过37℃的温生理盐水灌注恢复,缝合羊膜时要特别小心。结果:仔细应用这些技术,胎儿手术实验成功率达90%。结论:一种技术上简单的胎兔手术方法已经开发出来。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Techniques in fetal rabbit surgery].

Objective: Experimental fetal surgery has been a popular way to study growth and development and wound healing. The rabbit continues to be a reasonable animal model. The key to success of the experiment lies in keeping the survival rate of the operated animal above 80 percent. In this paper a simple experimental method for fetus surgery in rabbits is described.

Methods: Intravenous thiopental sodium is used for general anesthesia. Surgery is performed inside the uterus through hysterotomy or with the caudal part of the fetus out of the uterus. Amniotic fluid is restituted by instillation of warm saline at 37 degrees C. Special care is taken to suture the amnion.

Results: Using these techniques carefully, we have had 90 percent of success in fetal surgery experiment.

Conclusion: A technically simple procedure has been developed for fetal rabbit surgery.

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